Non-inferiority designs comparing placebo to a proven therapy for childhood pneumonia in low-resource settings.

CONCLUSION: In the setting where the benefit of a previously established beneficial treatment is questioned, a non-inferiority design that includes placebo as the tested treatment option can be the most appropriate design option.
PMID: 31814441 [PubMed - as supplied by publisher]

Source: Clinical Trials - December 7, 2019 Category: Research Authors: May S, Brown SP, Schmicker RH, Emerson SS, Nkwopara E, Ginsburg AS Tags: Clin Trials Source Type: research