Gender and Age Differences and the Trend in the Incidence and Prevalence of Dementia and Alzheimer's Disease in Taiwan: A 7-Year National Population-Based Study.

This study aims to describe the gender and age differences in the incidence and prevalence of dementia and AD in Taiwan. Methods: The data on dementia and AD were acquired from the Taiwan National Health Insurance Research Database from 2004 to 2010. The sex and age-specific rates were standardized, and the differences of gender and age on dementia or AD were assessed using Poisson regression analysis. Results: Over seven years, the prevalence of dementia and AD significantly increased from 4.7 to 7.6 per hundred people (β = 0.0784, p
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research

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While most patients with Alzheimer's and Related Dementias (ADRD) prefer to die in nursing facilities, trends and factors associated with place of death for this population remain unknown.
Source: Journal of Pain and Symptom Management - Category: Palliative Care Authors: Source Type: research
Authors: Sun F, Chima E, Wharton T, Iyengar V Abstract Alzheimer's disease and related dementias (ADRD) affect over 50 million persons globally, and the number is expected to rise. In response, health ministries are developing and implementing policies and programs to systemically address the needs of individuals and families affected by ADRD. While national plans of action on ADRD are advancing among European Member States of World Health Organization (WHO), those in the Asia-Pacific and Americas are lagging behind. Since previous studies have largely ignored the Americas and Asia-Pacific-where approximately two-t...
Source: Pan American Journal of Public Health - Category: International Medicine & Public Health Tags: Rev Panam Salud Publica Source Type: research
AbstractMid-life hypertension and cerebrovascular dysfunction are associated with increased risk of later life dementia, including Alzheimer ’s disease (AD). The classical renin–angiotensin system (cRAS), a physiological regulator of blood pressure, functions independently within the brain and is overactive in AD. cRAS-targeting anti-hypertensive drugs are associated with reduced incidence of AD, delayed onset of cognitive decline, a nd reduced levels of Aβ and tau in both animal models and human pathological studies. cRAS activity is moderated by a downstream regulatory RAS pathway (rRAS), which is undera...
Source: Acta Neuropathologica - Category: Neurology Source Type: research
AIM: The clock drawing test (CDT) is widely used as a visual spatial ability test and screening test for dementia patients. The appearance frequency of qualitative errors obtained through the qualitative analysis of CDT may be related to the participant's ...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Age: Elder Adults Source Type: news
Dementia is a global health problem, with the World Health Organization estimates placing the number of afflicted persons at around 50 million worldwide.1 Without a treatment or cure, projections are that numbers will increase dramatically around the world by 2050.2 The prevalent intervention strategy has been pursuit of a drug to cure this illness or to modify the illness course. Available medications, mainly approved for use in Alzheimer's-type dementia (AD) but extended empirically to other forms, are mainly palliative with only modest benefits in a subset of patients.
Source: Journal of the American Medical Directors Association - Category: Health Management Authors: Tags: Editorial Source Type: research
Title: When Dementia Harms Speech, Native Language MattersCategory: Health NewsCreated: 1/22/2020 12:00:00 AMLast Editorial Review: 1/23/2020 12:00:00 AM
Source: MedicineNet Alzheimer - Category: Geriatrics Source Type: news
(University of British Columbia) Living near major roads or highways is linked to higher incidence of dementia, Parkinson's disease, Alzheimer's disease and multiple sclerosis (MS), suggests new research published this week in the journal Environmental Health.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Molecules, Vol. 25, Pages 503: White Matter and Neuroprotection in Alzheimer’s Dementia Molecules doi: 10.3390/molecules25030503 Authors: Lorenzini Fernandez Baldassarro Bighinati Giuliani Calzà Giardino Myelin is the main component of the white matter of the central nervous system (CNS), allowing the proper electrical function of the neurons by ensheathing and insulating the axons. The extensive use of magnetic resonance imaging has highlighted the white matter alterations in Alzheimer’s dementia (AD) and other neurodegenerative diseases, alterations which are early, exten...
Source: Molecules - Category: Chemistry Authors: Tags: Review Source Type: research
CONCLUSION: Specialised home palliative care services may be suboptimal, and primary care services may serve as a key access point in providing baseline palliative care to people with conditions needing palliative care. Therefore, primary care services should aim to enhance their palliative care workforce. PMID: 31971075 [PubMed - as supplied by publisher]
Source: Palliative Medicine - Category: Palliative Care Authors: Tags: Palliat Med Source Type: research
Frailty and cognitive impairment are among the two most common geriatric syndromes. Their presence poses major risks to the elderly including greater disability, reduced quality of life, and higher morbi-mortality. Recent evidence suggest that frailty can be a risk factor for incident dementia. The opposite is also true since subjects with Alzheimer's disease and other dementia also present with more severe frailty measures. The mechanisms for the association between frailty and cognitive impairment is not clear, but possibly involves abnormalities in biological processes related to aging.
Source: Translational Research - Category: Research Authors: Tags: Review Article Source Type: research
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