Disinfectant potential in inactivation of epidemic keratoconjunctivitis-related adenoviruses by potassium peroxymonosulfate.
CONCLUSION: This study demonstrated that potassium peroxymonosulfate is a promising disinfectant for the prevention of epidemic keratoconjunctivitis nosocomial infections in ophthalmological clinics. PMID: 31813297 [PubMed - as supplied by publisher]
Abstract In deterministic models of epidemics, there is a host abundance threshold above which the introduction of a few infected individuals leads to a severe epidemic. Studies of weather-driven animal pathogens often assume that abundance thresholds will be overwhelmed by weather-driven stochasticity, but tests of this assumption are lacking. We collected observational and experimental data for a fungal pathogen, Entomophaga maimaiga, that infects the gypsy moth, Lymantria dispar. We used an advanced statistical-computing algorithm to fit mechanistic models to our data, such that different models made different ...
Conclusions: Certain groups were more likely to underestimate risks of mixing opioid pain-relievers with alcohol or benzodiazepines. Results underscore the importance of targeted public awareness campaigns, prevention programing, and communication between physicians and patients about the risks of mixing substances, particularly among high-risk groups. PMID: 32091310 [PubMed - as supplied by publisher]
Publication date: Available online 25 February 2020Source: Preventive Veterinary MedicineAuthor(s): Lívian Otávio Lecca, Marcelo Teixeira Paiva, Camila Stefanie Fonseca de Oliveira, Maria Helena Franco Morais, Maria Isabel de Azevedo, Camila de Valgas e Bastos, Kelly Moura Keller, Roselene Ecco, Márcia Regina Silva Alves, Graziella Coelho Tavares Pais, Lauranne Alves Salvato, Gustavo de Morais Donancio Xaulim, David Soeiro Barbosa, Silvana Tecles Brandão, Danielle Ferreira de Magalhães Soares
Alcohol-induced deaths in the US have increased substantially over the years and have recently accelerated, prompting calls for urgent action.Medscape Medical News
Publication date: Available online 25 February 2020Source: Molecular and Cellular ProbesAuthor(s): Lan-Lan Zheng, Jian-Tao Cui, Hao-Ying Han, Hua-Lin Hou, Le-Yi Wang, Fang Liu, Hong-Ying Chen
This article is licensed under aCreative Commons Attribution 3.0 Unported Licence.Joshua P. Barham, Thierry N. J. Fouquet, Yasuo Norikane Base-catalyzed, C-Alkylation of potassium (K) Enolates with Syrenes (CAKES) enables practical synthesis or elaboration of pharmaceutical coresvia a thusfar elusive mechanism. Herein, computational (DFT) and kinetic studies back a metal-ene reaction. To cite this article before page numbers are assigned, use the DOI form of citation above. The content of this RSS Feed (c) The Royal Society of Chemistry
Okay, I'm not an epidemiologist or a virologist. But I do know something about those subjects, I'm a public health professor, and I am an expert in clinical communication and risk communication. So I'm going to offer some observations that I hope will help people keep this public health scare in proper perspective and maybe be of practical use.There are two important parameters we need to understand the risk caused by any communicable disease. I'm going to broadly say transmissibility, and the probability that exposure will lead to serious disease.We often see transmissibility represented as a single number, called R0 or &...
CONCLUSIONS Our data highlight several areas of concern in the practice of standard or transmission-based precautions in the sampled population. First, hand-hygiene policies are not well enforced. Second, personal protective equipment is not appropriately used while examining potentially infectious patients. Third, eye-drop vials are not consistently discarded if contaminated with eye secretions. Lastly, a large proportion of surveyed practices use inadequate disinfection techniques of tonometers.
In this study, we sought to investigate whether SH0165 (serovar 5, high-virulent strain) and HN0001 (serovar 6, non-virulent strain) infection induces autophagy and the specific role of autophagy in bacterial invasion and inflammation during H. parasuis infection. Moreover, we explored the mechanism underlying autophagy regulated inflammation through inflammatory signaling cascades during H. parasuis infection. This observation could provide useful information for further understanding the role of autophagy in H. parasuis infection and improve our knowledge of new strategies against this pathogen. Materials and Methods B...
ConclusionThe alcohol-based solutions tested in this study were not found to be sufficiently effective against adenovirus serotypes. Further studies to investigate the efficiency of different alcohol-based solutions are required.