Exceptional response of brain metastases to short course nivolumab while on high-dose steroids.

Exceptional response of brain metastases to short course nivolumab while on high-dose steroids. Neth J Med. 2019 Dec;77(9):338-340 Authors: de Jong WK, Mulders ACM, Westendorp W, Becker A Abstract In this manuscript, we describe a patient with an exceptional response of brain metastases from lung cancer to short course nivolumab while on high-dose steroids. This case shows that immunotherapy can cause delayed and enduring responses even in patients with poor predictive parameters for treatment success, such as low programmed death ligand-1 (PDL1) expression and long-term treatment with high-dose corticosteroids. Secondly, it underscores the importance of follow up after the administration of immunotherapy, even in cases with a deemed poor prognosis and few received cycles of immunotherapy. PMID: 31814589 [PubMed - in process]
Source: The Netherlands Journal of Medicine - Category: General Medicine Authors: Tags: Neth J Med Source Type: research