Genes, Vol. 10, Pages 1031: Delineation of Homozygous Variants Associated with Prelingual Sensorineural Hearing Loss in Pakistani Families

This study further highlights the challenges of identifying disease-causing variants for highly heterogeneous disorders and reports the identification of three novel and four previously reported variants in seven known deafness genes.
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Communication Source Type: research

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Source: Hearing, Balance and Communication - Category: Audiology Authors: Source Type: research
Authors: Yang S, Chen S, Zhu J, Han X PMID: 31942778 [PubMed]
Source: Journal of Clinical Neurology - Category: Neurology Tags: J Clin Neurol Source Type: research
Provision of sign language courses for parents of deaf children is found to be "patchy".
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
Provision of sign language courses for parents of deaf children is found to be "patchy".
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
On this episode of ASHA Voices, we dive into the research behind hearing loss reversal. While investigating a genetic form of hearing loss affecting transduction, researcher Jeff Holt  found he could successfully reverse hearing loss in mice. How did the researcher test the rodents’ hearing? By unexpectedly playing loud music and looking for a response in the subjects, nicknamed Beethoven mice. “A deaf mouse doesn’t jump at all, no matter how loud a sound you play. But after introducing our gene therapy into the ears of Beethoven mice, we find they jump again,” says Holt. Also on the show, sens...
Source: American Speech-Language-Hearing Association (ASHA) Press Releases - Category: Speech-Language Pathology Authors: Tags: Academia & Research Audiology Health Care Podcast Slider Speech-Language Pathology ASHA Convention audiologist Hearing Assistive Technology hearing loss Source Type: blogs
AbstractBackgroundDeaf people experience health inequalities compared to hearing populations. The EQ-5D, a widely used, standardised, generic measure of health status, which is available in over 100 languages, was recently translated into British Sign Language (BSL) and initial validation conducted. Using data from this previous study of the EQ-5D-5L BSL we aimed to assess (1) whether responses to the EQ-5D differed between a sample of Deaf BSL users and the general population (2) whether socio-demographic characteristics and clinical measures were associated with EQ-5D index scores in Deaf BSL users and (3) the impact of ...
Source: Applied Health Economics and Health Policy - Category: Health Management Source Type: research
ConclusionsFindings from this 2019 study indicate that deaf or hard of hearing women are at a heightened risk for chronic conditions, pregnancy-related complications, and adverse birth outcomes and underscore the need for systematic investigation of the pregnancy- and neonatal-related risks, complications, costs, mechanisms, and outcomes of deaf or hard of hearing women.
Source: American Journal of Preventive Medicine - Category: International Medicine & Public Health Source Type: research
Conclusion Even at moderate levels of parenting stress similar to parents of children with normal hearing, increases in parenting stress were associated with lower scores on our measures of language comprehension and inhibitory control in children with HL. Thus, parenting stress may underlie some of the variability in at-risk pediatric HL outcomes. PMID: 31940261 [PubMed - as supplied by publisher]
Source: Journal of speech, language, and hearing research : JSLHR - Category: Speech-Language Pathology Authors: Tags: J Speech Lang Hear Res Source Type: research
Publication date: Available online 13 January 2020Source: Neuroscience LettersAuthor(s): Yu Zheng, Wenwei Luo, Rui Ma, Ning Cong, Dongdong Ren, Fanglu Chi, Juanmei YangAbstractPrevious reports have suggested that the level and duration of Atoh1 expression are correlated with the survival, arrangement and stereociliary bundle-related morphology of hair cells during development, but whether Atoh1 expression levels are correlated with the arrangement, bundle formation and electrophysiological characteristics of newly formed hair cells is unknown. To address this question, cultured cochlear explants obtained from neonatal rats...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
A disabled woman is in an Ontario court this week seeking changes to Canada's student loan program that she argues would level the playing field for people with disabilities.
Source: CBC | Health - Category: Consumer Health News Tags: News/Canada/Toronto Source Type: news
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