Mink Aleutian disease seroprevalence in China during 1981–2017: A systematic review and meta-analysis

Publication date: Available online 10 December 2019Source: Microbial PathogenesisAuthor(s): Qing-Long Gong, Dong Li, Nai-Chao Diao, Yi Liu, Bo-Yu Li, Tian Tian, Gui-Yang Ge, Bo Zhao, Yu-Hao Song, Dong-Li Li, Xue Leng, Rui DuAbstractMink Aleutian disease (AMD) is the first of the three major diseases of fur animals. It is a common immunosuppressive disease in mink farms worldwide, which seriously endangers the development of the mink farming industry. Strengthening the understanding of the positive serum rate and spatial distribution of AMD is of great significance for the prevention and control of disease caused by the Aleutian virus. Therefore, we conducted a systematic review and meta-analysis to assess the seroprevalence of AMD in China. We extracted 45 studies related to the seroprevalence of Chinese AMD, with samples taken between 1981 and 2017. Our systematic review and meta-analysis results show that, during the selected period, the overall positive rate of AMD in China was 55.3% (95% CI 48.5–62.0). The results from subgroups analysis of the potential risk factors showed that the seroprevalence rate of AMD in China in the past 36 years rose from 48% (95% CI 37.0–60.5) in 1981–2009 to 61.4% (95% CI 43.6–79.3) in 2010–2017. The date of the spatial difference in AMD seroprevalence indicated that AMD seroprevalence was unevenly distributed in different regions: the number of mink in eastern China and northeastern China was relatively high, and the seroprevalence ...
Source: Microbial Pathogenesis - Category: Infectious Diseases Source Type: research