Probiotic yeast may offer an effective treatment for drug-resistant fungal infections

(Worcester Polytechnic Institute) Researchers at Worcester Polytechnic Institute (WPI)&the Central Food Technological Research Institute in India are studying the effect of probiotic yeast in preventing fungal infections.
Source: EurekAlert! - Infectious and Emerging Diseases - Category: Infectious Diseases Source Type: news

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(Natural News) While it’s true that human zombies still remain in the realm of science fiction, their insect counterparts have been known to science for quite a while. A recent study took a closer look at one of the more macabre causes of this phenomenon: a deadly fungus that turns cicadas into sex zombies as it rots their genitals and...
Source: - Category: Consumer Health News Source Type: news
Authors: Wang S, Shang J, Xiao J, Zhao Z Abstract Aims: The aim was to determine whether anti-neutrophil cytoplasmic antibody (ANCA)-positive serology in patients with lupus nephritis (LN) is associated with different clinicopathologic features and outcomes.Methods: In our retrospective analysis, 283 patients were enrolled between 2013 and 2018. Thirty-six patients were ANCA-positive, and this group was compared with the remaining 247 patients who were confirmed as ANCA-negative at the time of biopsy.Results: ANCA-positive LN patients exhibited higher anti-dsDNA antibody titers and serum creatinine levels and lower...
Source: Renal Failure - Category: Urology & Nephrology Tags: Ren Fail Source Type: research
Conclusion: Although Fusarium keratitis remains a rare complication of CL wear, we found a significant increase of cases in the Netherlands. The course of infection may be severe and fungal diagnosis was often delayed. Antifungal treatment strategies varied widely and the treatment failure rate was high, requiring transplantation or even enucleation. Our study underscores the need for systematic surveillance of fungal keratitis and a consensus management protocol.
Source: Frontiers in cellular and infection microbiology - Category: Microbiology Source Type: research
Ventricular assist device (VAD) infections are an important cause of morbidity and mortality. Fungal infections are associated with poor outcomes and risk factors to predict infection warrant characterization.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (1250) Source Type: research
Invasive fungal infection (IFI) remains one of the most common complications after heart and lung transplantation, which relates to high morbidity and mortality rates. However, risk factors associated with this infection have not been well demonstrated.
Source: The Journal of Heart and Lung Transplantation - Category: Transplant Surgery Authors: Tags: (1241) Source Type: research
This study describes a case of disseminated phaeohyphomycosis caused by C. ludoviensis in Iran. The molecular identification of the isolates was established by DNA sequencing of the internal transcribed spacer (ITS) region of rDNA. The patient was successfully treated with an 8-month course of systemic voriconazole. PMID: 32236938 [PubMed - as supplied by publisher]
Source: The Australasian Journal of Dermatology - Category: Dermatology Authors: Tags: Australas J Dermatol Source Type: research
Publication date: 15 August 2020Source: Food Chemistry, Volume 321Author(s): Ye Sun, Renfu Lu, Leiqing Pan, Xiaochan Wang, Kang Tu
Source: Food Chemistry - Category: Food Science Source Type: research
Cryptococcus meningitis (CM) is a subacute or chronic deep fungal infection of central nervous system, which is the most severe clinical manifestation caused by cryptococcus (Mpoza et al., 2019). The epidemiological data of the foreign countries show that the acquired immunodeficiency syndrome (AIDS) - related CM is more common (Bennett et al., 1979; Dismukes et al., 1987; Pappas et al., 2001; Mirza et al., 2003; Dromer et al., 2007 ), but the epidemiological data in China show that 50-77% of patients with CM have normal immune function (Lu et al., 1999; Kombila et al., 2016; Yao et al., 2005; Lui et al., 2006; Zhu et al.,...
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Source Type: research
AbstractOnychomycosis is a difficult-to-treat fungal infection of the human nail plate or bed that primarily affects the natural anatomy of human toe and finger nails, leading to a hard, brittle, and uneven nail surface. The severe structural mutilation of nails restricts the application of conventional formulations and makes onychomycosis therapy a challenging clinical premise. Oral therapy with drugs such as terbinafine hydrochloride and itraconazole may lead to drug interactions and systemic adverse effects, whereas topical treatment with drugs such as ciclopirox olamine and amorolfine are often associated with poor dru...
Source: Drugs and Therapy Perspectives - Category: Drugs & Pharmacology Source Type: research
Abstract The Fungal infections are diseases that are considered neglected although their infection rates have increased worldwide in the last decades. Thus, since the antifungal arsenal is restricted and many strains have shown resistance new therapeutic alternatives are necessary. Nanoparticles are considered important alternatives to promote drug delivery. In this sense, the objective of the present study was to evaluate the contributions of newly developed nanoparticles to the treatment of fungal infections. Studies have shown that nanoparticles generally improve the biopharmaceutical and pharmacokinetic charac...
Source: Current Medicinal Chemistry - Category: Chemistry Authors: Tags: Curr Med Chem Source Type: research
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