Ketamine sedation in mechanically ventilated patients: A systematic review and meta-analysis

ConclusionsThe data regarding ketamine use in mechanically ventilated patients is limited in terms of quantity, methodological quality, and demonstrated clinical benefit. Ketamine may play a role as a sedative-sparing agent, but may be associated with harm. High-quality studies are needed before widespread adoption of ketamine earlier in the sedation pathway.
Source: Journal of Critical Care - Category: Gastroenterology Source Type: research