MiR-21-5p inhibits the progression of human chondrosarcoma by regulating CCR7/STAT3/NF- κB pathway.
Conclusion: miR-21-5p targeted CCR7 expression to inhibit the STAT3 and NF-κB signaling, thereby suppressing cell proliferation, migration, invasion and EMT in CS cells, which might be a novel mechanistic study for CS therapy.
PMID: 31813289 [PubMed - as supplied by publisher]
Source: Connective Tissue Research - Category: Research Tags: Connect Tissue Res Source Type: research