Safety and Efficacy of Immune Checkpoint Inhibitors in Patients With Cancer and Preexisting Autoimmune Disease: A Nationwide, Multicenter Cohort Study

ConclusionOur findings indicate that flares or IRAEs occur frequently but are mostly manageable without ICI discontinuation in patients with a preexisting autoimmune disease. Immunosuppressive therapy at baseline is associated with poorer outcomes.

Source: Arthritis and Rheumatology - November 27, 2019 Category: Rheumatology Authors: Alice Tison, Gilles Qu éré, Laurent Misery, Elisa Funck‐Brentano, François‐Xavier Danlos, Emilie Routier, Caroline Robert, Yohann Loriot, Olivier Lambotte, Bertille Bonniaud, Camille Scalbert, Sarah Maanaoui, Thierry Lesimple, Stéphan Tags: Original Article Source Type: research