Dallas children's hospital relocates 28 patients after tests find mold

Positive mold tests at Children's Medical Center Dallas propmpted the facility to relocate 28 patients. Routine air tests showed higher-than-normal levels of Aspergillus and Penicillium molds, which are generally not harmful except to those with compromised immune systems.
Source: CNN.com - Health - Category: Consumer Health News Source Type: news

Related Links:

Publication date: Available online 15 January 2020Source: Protein Expression and PurificationAuthor(s): Uriel Rojas-Sánchez, Alberto Cristian López-Calleja, Blanca E. Millán-Chiu, Francisco Fernández, Achim M. Loske, Miguel A. Gómez-LimAbstractAspergillus niger has been employed to produce heterologous proteins due to its high capacity for expression and secretion; nevertheless, expression levels of human proteins have been modest. We were interested in investigating whether A. niger can express and secret human erythropoietin (HuEPO) at high yields. Our strategy was to combine the presen...
Source: Protein Expression and Purification - Category: Biochemistry Source Type: research
In this study, we reviewed in-vitro and in-vivo studies, as well as clinical reports pertaining to the antifungal efficacy of statins. In addition, we have addressed various modulators of statin anti-fungal activity and the potential mechanisms responsible for their anti-fungal effects. In general, statins do possess anti-fungal activity, targeting a broad spectrum of fungal organisms including human opportunistic pathogens such as Candida spp. and Zygomycetes, Dermatophytes, alimentary toxigenic species such as Aspergillus spp., and fungi found in device implants such as Saccharomyces cerevisiae. Statins have been shown t...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
o Park Kap-Hoon Han The velvet regulator VosA plays a pivotal role in asexual sporulation in the model filamentous fungus Aspergillus nidulans. In the present study, we characterize the roles of VosA in sexual spores (ascospores) in A. nidulans. During ascospore maturation, the deletion of vosA causes a rapid decrease in spore viability. The absence of vosA also results in a lack of trehalose biogenesis and decreased tolerance of ascospores to thermal and oxidative stresses. RNA-seq-based genome-wide expression analysis demonstrated that the loss of vosA leads to elevated expression of sterigmatocystin (ST) biosynthe...
Source: Genes - Category: Genetics & Stem Cells Authors: Tags: Article Source Type: research
AbstractAirborne bacteria and fungi in hospital environments are of great concern due to their potential role as a source of nosocomial infections. The aim of this study was to evaluate concentration and diversity of airborne bacteria and fungi in relation to particle mass concentration in sensitive wards of a pediatric hospital. The study was performed in the cardiac care unit (CCU), the neonatal intensive care unit  (NICU), the cancer blood ward (BW), the ENT (ear, nose, throat) operation room (OT1) and the eye operation room (OT2). The air samples were collected by impaction using the single-stage Anderse...
Source: Aerobiologia - Category: Environmental Health Source Type: research
In this study, to further explore the function of DevR, its interaction proteins were screened by a yeast two-hybrid assay. An A. oryzae cDNA library was transformed into the Y187 strain by using the SMART technique and the homologous recombination method, and then hybridized witha constructed DevR bait plasmid introducing strain to obtain positive clones. Through sequencing analysis, the potential interaction proteins of DevR were determined. Among them, an AO090701000363 gene-encoding protein (named DipA), which was predicted to be a basic leucine zipper (bZIP) transcription factor, was a possible candidate. Phenotypic a...
Source: Fungal Biology - Category: Biology Source Type: research
.
Source: Mycology - Category: Biology Authors: Source Type: research
Contributors : James I Stewart ; Vinicius M Fava ; Joshua D Keraert ; Adithya S Subramanian ; Fabrice N Gravelat ; Melanie Lehoux ; P L Howell ; Robert A Cramer ; Donald C SheppardSeries Type : Expression profiling by high throughput sequencingOrganism : Aspergillus fumigatusInhalation of conidia of the opportunistic mold  Aspergillus fumigatus by immunocompromised hosts can lead to invasive pulmonary disease. Inhaled conidia that escape immune defenses germinate to form filamentous hyphae that invade lung tissues. Conidiation rarely occurs during invasive infection of the human host, allowing the bulk of fungal ...
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Aspergillus fumigatus Source Type: research
Aspergillus flavus is an ascomycete fungus that infects and contaminates corn, peanuts, cottonseed, and treenuts with acutely toxic and carcinogenic aflatoxins. The ecological function of aflatoxin production is not well understood; though not phytotoxic, aflatoxin may be involved in resisting oxidative stress responses from infection or drought stress in plants. Observation of aflatoxin stimulation in 48-well plates in response to increasing inoculated wells sparked an investigation to determine if A. flavus volatiles influence aflatoxin production in neighboring colonies. Experiments controlling several culture condition...
Source: Frontiers in Microbiology - Category: Microbiology Source Type: research
In this study, we investigated the chemical composition and the cytotoxic, antimicrobial, and anti-inflammatory activities of the fruit peel essential oil of S. pinnata (EOSP), which has been consumed as a medicine and condiment in Xishuangbanna, southwest China. A total of 40 components were identified by Gas Chromatography/Mass spectrometry (GC-MS), representing 95.19% of the EOSP, with furfural (17.14%), α-terpineol (13.09%), and ethyl benzoate (9.05%) as the main constituents. EOSP has moderate cytotoxic activity against five cancer cells and obvious antimicrobial activity against five pathogenic strains. In ...
Source: Molecules - Category: Chemistry Authors: Tags: Article Source Type: research
ConclusionsThis is the first report of a patient with inherited CARD9 deficiency and chronic invasive pulmonary aspergillosis (IPA) due toA. nomius. Inherited CARD9 deficiency should be considered in otherwise healthy children and adults with one or more invasive fungal diseases.
Source: Journal of Clinical Immunology - Category: Allergy & Immunology Source Type: research
More News: Aspergillus | Children | Health | Hospitals