URB597 protects against NLRP3 inflammasome activation by inhibiting autophagy dysfunction in a rat model of chronic cerebral hypoperfusion

Previous studies reported that URB597 (URB) had therapeutic potential for treating chronic cerebral hypoperfusion (CCH)-induced neuroinflammation and autophagy dysfunction. However, the interaction mechanisms ...

Source: Journal of Neuroinflammation - December 9, 2019 Category: Neurology Authors: Shao-Hua Su, Yi-Fang Wu, Qi Lin, Da-Peng Wang and Jian Hai Tags: Research Source Type: research