Nigeria: Malaria - EU/Unicef Programme Treats 16,992 Children in Adamawa
[Premium Times] No fewer than 16,992 children below the age of five were treated of malaria under the EU/UNICEF Maternal, New-born and Child Health and Nutrition (MNCHN) project in Adamawa.
[The Conversation Africa] Kenya experienced above-average rainfall since October 2019, causing landslides and deaths. Some rivers burst their banks and dams overflowed for the first time in years.
[Nation] One person has died while 135 others have been treated for Malaria in Elgeyo-Marakwet in the last one week as the disease spreads amidst the lack of drugs in the county.
Conclusion: Due to general lack of awareness towards toxoplasmosis observed among both health workers and pregnant women in Temeke Municipality, we recommend health policy on maternal and child healthcare to address prenatal screening that is aimed at providing early diagnosis for any possible congenital toxoplasmosis as well as diseases that are currently screened in Tanzania such as HIV, syphilis and malaria. Integrating a One Health approach in educating medical professionals and the vulnerable population of pregnant women on the importance of congenital zoonoses will promote awareness and preventive practices towards t...
[East African] The Global Fund, the body that finances the world's HIV, tuberculosis (TB) and malaria programmes, has given Kenya Ksh42 billion ($420 million) to cover the intervening years to 2024.
(Barcelona Institute for Global Health (ISGlobal)) A group of experts led by Regina Rabinovich and Carlos Chaccour from the Barcelona Institute for Global Health (ISGlobal) has published a roadmap to evaluate -- and subsequently implement -- ivermectin as a complementary vector control tool against malaria. The Ivermectin Roadmap, published in the American Journal of Tropical Medicine and Hygiene, includes a foreword signed by Nobel laureate William C. Campbell, co-discoverer of the drug.
Date: Tuesday, 01 28, 2020; Speaker: Ricardo T. Gazzinelli, Professor, University of Massachusetts Medical School; 12735 Twinbrook Pkwy; 2nd Floor Conference Room
Conclusions: This first detailed characterization of novel EXP1-specific T cell epitopes provides important information for future analysis with major histocompatibility complex-multimer technology as well as for immunomonitoring and vaccine design.
The distributions of human malaria parasite species overlap in most malarious regions of the world, and co-infections involving two or more malaria parasite species are common. Little is known about the consequences of interactions between species during co-infection for disease severity and parasite transmission success. Anti-malarial interventions can have disproportionate effects on malaria parasite species and may locally differentially reduce the number of species in circulation. Thus, it is important to have a clearer understanding of how the interactions between species affect disease and transmission dynamics. Cont...
In this study, we investigated combining two liver-stage antigens, P. falciparum LSA1 (PfLSA1) and PfLSAP2, and investigated the induction of protective efficacy by coadministration of single-antigen vectors or vaccination with dual-antigen vectors, using simian adenovirus and modified vaccinia virus Ankara vectors. The efficacy of these vaccines was assessed in mouse malaria challenge models using chimeric P. berghei parasites expressing the relevant P. falciparum antigens and challenging mice at the peak of the T cell response. Vaccination with a combination of the single-antigen vectors expressing PfLSA1 or PfLSAP2 was ...
This study highlights ThPOK as a global regulator of immune function in which alterations may affect normal responses to infectious and inflammatory stimuli.