Acute Kidney Recovery in Patients Undergoing Transcatheter Versus Surgical Aortic Valve Replacement (From the Northern New England Cardiovascular Disease Study Group)
We examined patients with chronic kidney disease and severe aortic stenosis undergoing SAVR or TAVR procedure between 2007-2017; excluding age90, dialysis, endocarditis, non-aortic valve stenosis, or patients died within 48-hours post-procedure.
Publication date: Available online 20 January 2020Source: LWTAuthor(s): Derong Lin, Xiaomei Long, Yichen Huang, Yuanmeng Yang, Zhijun Wu, Hong Chen, Qing Zhang, Dingtao Wu, Wen Qin, Zongcai TuAbstractThe effects of mixed fermentation by lactic acid bacteria and Neurospora crassa, and microwave treatment on the composition, structure, and functional properties of okara DF were studied. The results of SEM and EDX showed that the honeycomb structure was more obvious and the content of elemental components was changed after fermentation and microwave treatment. The result of TGA-DSC showed that the thermal stability of the sam...
Publication date: Available online 21 January 2020Source: American Journal of Kidney DiseasesAuthor(s): Dana Miskulin, Daniel E. Weiner, Harold J. Manley
Publication date: Available online 21 January 2020Source: American Journal of Kidney DiseasesAuthor(s): Anne M. Butler, J. Bradley Layton, Vikas R. Dharnidharka, Leah J. McGrath
Publication date: Available online 20 January 2020Source: American Journal of Kidney DiseasesAuthor(s): Yvelynne P. Kelly, Gilad J. Kuperman, David J.R. Steele, Mallika L. Mendu
Around 850 million people currently are affected by different types of kidney disorders.1 Up to 1 in 10 adults worldwide has chronic kidney disease (CKD), which is invariably irreversible and mostly progressive. The global burden of CKD is increasing, and CKD is projected to become the fifth most common cause of years of life lost globally by 2040.2 If CKD remains uncontrolled and if the affected person survives the ravages of cardiovascular and other complications of the disease, CKD progresses to end-stage kidney disease, where life cannot be sustained without dialysis therapy or kidney transplantation.
Much of medical data is buried in the free text of clinical notes and not captured by structured data, such as administrative codes. Natural language processing (NLP) can locate and use information that resides in unstructured free text. Chan et al. demonstrate that NLP is sensitive for identifying symptoms in hemodialysis patients. These findings highlight the benefit NLP may bring to nephrology and should prompt discussion of important considerations for NLP system design and implementation.
Although our Dialysis Outcomes and Practice Patterns Study reported a relatively slow international decrease of hepatitis C virus (HCV) prevalence and incidence in hemodialysis (HD) units from 1996 to 20121 (before the direct-acting antiviral era), Huang et al. now report their direct-acting antiviral–based elimination of HCV from a single HD unit in Taiwan.2 Such eradication of HCV will reduce the clinical burden associated with HCV infection. In addition, HCV eradication should prevent HCV nosocomial transmission.
We read the report by Jadoul et al.1 with great interest in a recent issue in Kidney International. The World Health Organization has set ambitious goals for hepatitis C virus (HCV) eradication using the “micro-elimination” approach.2 Taiwan has one of the highest prevalence and incidence of end-stage kidney disease worldwid e. HCV infection is an important complication among our hemodialysis patients.3 With the advent of the new direct-acting antivirals, complete eradication of HCV infection is one of our key priorities.
Potassium channels are important to control membrane potential and drive epithelial transport processes. In this issue of Kidney International, Bignon et al. report the role of the Kir4.2 K+-channel, localized at the basolateral membrane of proximal tubules, in the reabsorption of bicarbonate and the modulation of renal ammoniagenesis. The findings have implications for our understanding of how the kidney reacts to hypokalemia, an acid load, and th e metabolic acidosis of patients with advanced stages of chronic kidney disease.
Acute kidney recovery (AKR) is a recently described phenomenon observed after transcatheter aortic valve replacement (TAVR) and is more frequent than acute kidney injury (AKI). To determine the incidence and predictors of AKR between surgical aortic valve replacement (SAVR) and TAVR, we examined patients with chronic kidney disease and severe aortic stenosis who underwent SAVR or TAVR procedure between 2007 and 2017; excluding age90, dialysis, endocarditis, non-aortic valve stenosis, or patients died within 48-hours postprocedure.