Lappaconitine trifluoroacetate contained polyvinyl alcohol nanofibrous membranes: Characterization, biological activities and transdermal application

In conclusion, the prepared LAF-loaded membrane is a novel formulation for the treatment of chronic and long-term pain.Graphical abstract
Source: Materials Science and Engineering: C - Category: Materials Science Source Type: research

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With all the advances in modern medicine, it can be easy to wonder if there is a medication to stop drinking. Unfortunately, getting sober from alcohol isn’t as easy as simply taking medication. In addition to medication, therapy is required for the best long-term results, as well as support from loved ones and ongoing aftercare. However, there are some medications to help along in the process to stop withdrawal symptoms, block cravings, and create an aversion to alcohol. It is important to not rely only on medication to stop drinking. A commitment to behavioral therapy, holistic therapy, family involvement, self-ca...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Detox Resources for Alcohol and Drugs/Opiates alcohol abuse alcohol dependence alcohol detox alcohol treatment alcohol treatment center alcohol treatment facility Source Type: blogs
Abstract Many adults with opioid use disorder (OUD) report that their first exposure to opioids was in the course of routine pain treatment in medical care settings. Adolescents receive opioid prescriptions with frequency, but are susceptible to a constellation of unique risks in the context of pain management. This empirical study presents the first cohort of adolescents recruited from ambulatory medical care within 72 h of their receipt of opioids to treat acute pain. The primary aim was to capture a time-sensitive report of the intersection of prescription opioid receipt and contextual risks for opioid mis...
Source: Addictive Behaviors - Category: Addiction Authors: Tags: Addict Behav Source Type: research
Opioids are a class of drugs that include the illegal drug heroin, synthetic opioids such as fentanyl, and pain relievers available legally by prescription, such as oxycodone, hydrocodone, codeine, morphine, and many others. All individuals who take opioids run the risk of addiction. As such, when asking “what is an opioid?” it is important to know the different types, the signs of addiction, and the signs of an overdose. Prescription Opioids Opioids interact with the opioid receptors on nerve cells in the body and brain. This interaction interferes with communication between the body’s nerves and the br...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Detox Resources for Alcohol and Drugs/Opiates Heroin Painkiller fentanyl opioid opioid crisis opioids prescription drug addiction Source Type: blogs
Opioid Overdose: Signs, Symptoms, and What to Do Any individual who uses opioids runs the risk of overdosing. Overdoses can be fatal. In fact, more than 130 people in the United States die after overdosing on opioids every day. This makes it important to know what causes an opioid overdose, the signs that an opioid overdose is occurring, and what to do in the event of an opioid overdose. Opioid Overdose Causes In 2017, the CDC reported that more than 15,000 individuals died from drug overdoses involving heroin in the United States. That’s almost 5 deaths for every 100,000 Americans. However, there are some people who...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Detox Resources for Alcohol and Drugs/Opiates Painkiller drug overdose opiate addiction opioid opioids Source Type: blogs
According to a new report by Orange County, California’s health care agency, the overdose deaths in Orange County have greatly surpassed that of Los Angeles, Riverside, San Bernardino, San Diego, Ventura, and Santa Barbara counties and, most shockingly, all of California as a whole. The opioid crisis in Orange County has grown so much that a high concentration of treatment centers has popped up in the area hoping to combat this issue, but it doesn’t seem to be enough. In addition, the report details that the majority of state-licensed treatment centers and unregulated sober living homes are located along the c...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Detox Resources for Alcohol and Drugs/Opiates opiate abuse opiate addiction opioid opioid crisis opioids orange county Source Type: blogs
Opioids are so highly addictive that they have created a dangerous and deadly epidemic in the United States. In fact, the National Institute on Drug Abuse reports that more than 2 million Americans abuse opioids and that more than 90 Americans die on average by opioid overdose every day. Individuals can become addicted to opioids so quickly that it can be difficult to notice when the line has been crossed over to opioid abuse. If you or your loved one is taking opioids, whether legal or illegal, make note of these signs and symptoms of opioid abuse and how to get help. How Does Opioid Abuse Begin? Opioids work by binding ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Recovery Addiction to Pharmaceuticals Detox Resources for Alcohol and Drugs/Opiates abuse heroin heroin addiction heroin users opiate abuse opioid opioid crisis opioids prescription drug abuse prescription drug addiction Source Type: blogs
Learning more information about the addiction treatment process can be difficult if you do not know where to start looking. One of the many places individuals may begin their search is with their primary care provider, which makes it important to know how to ask your doctor about addiction treatment. There are many reasons an individual may seek addiction treatment advice from their doctor, including: The doctor is prescribing medications that they believe they have become addicted to The individual is suffering from a condition that they believe their addiction is worsening or impacting The individual doesn’t have...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Addiction Treatment and Program Resources doctor doctors treatment center treatment facilities treatment facility treatment options treatment programs Source Type: blogs
What are the Signs of Opioid Use? Opioids are a group of drugs derived naturally from the poppy plant, or are man-made in a laboratory, also known as synthetic opioids. Opioids are generally prescribed to individuals suffering from chronic pain, whether from surgery, a major injury or other health issues. Legally prescribed opioids include morphine, codeine, and oxycodone, while illegal opioids include heroin. It is easy to know if an individual is using opioids if they’ve been prescribed, but it is also important to know the signs of opioid use if it has crossed the line into an addiction. Signs and Symptoms There a...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals Painkiller opioid opioids prescription drug abuse prescription drug addiction prescription drug detox prescription drugs prescription medication signs of addiction Source Type: blogs
Opioid withdrawal is one of the more uncomfortable parts of treatment, but it is one of the most important. There are many signs of opioid withdrawal, the length and severity of which can vary from person to person. However, each detox experience almost always includes strong cravings. Symptoms can be mild, such as sweating and yawning, while others can become more serious, like severe anxiety and depression. Opioid withdrawal can look like a scary experience; one that could deter people from getting the help they need. The good news is that it doesn’t need to be fought alone, and there are resources available to ma...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Recovery Detox Resources for Alcohol and Drugs/Opiates drug detox medical detox medicated-assisted detox opioid opioids prescription drug detox withdrawal withdrawal symptoms Source Type: blogs
Cliffside Malibu does not condone the use of the term “addict” when referring to people suffering from the disorder of addiction. However, we do understand that others still may use the term in order to find information. Many people may find themselves asking the question, “am I an opioid addict?” if they feel as if their use has spiraled out of control. There are many ways to find out if you may have become addicted to opioids, as well as ways to get help and find treatment. How Opioid Addiction Begins Nearly 80% of heroin users started with prescription opioids, which puts prescription drugs and ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction to Pharmaceuticals addiction treatment opioid opioid crisis opioids pharmaceutical addiction pharmaceutical drug abuse treatment Source Type: blogs
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