Aspirin may no longer be effective as cardiovascular treatment

(Oxford University Press USA) A new paper in Family Practice, published by Oxford University Press, found that the widespread use of statins and cancer screening technology may have altered the benefits of aspirin use. Researchers concluded that aspirin no longer provides a net benefit as primary prevention for cardiovascular disease and cancer.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news

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Telephone intervention linked to rise in men ’s vegetable consumption but not to drop in risk of progression Related items fromOnMedica Less regular PSA screening puts men at risk NICE guidance delays hinder good diabetes care Population weight control best for cutting diabetes prevalence Starting statins not beneficial in many older adults NHS must hold CCGs accountable for poor diabetes care
Source: OnMedica Latest News - Category: UK Health Source Type: news
Whether you have a stomachache, a wrist sprain or a chronic disease, one of the first things doctors and nurses will do at an appointment is take your temperature. A normal temperature means your body is humming along the way it should. A higher temperature means you have a fever, and shows your body could be fighting an infection. And since 1871, “normal” has meant 98.6°F (37°C). That number was determined by a German physician, based on millions of readings from 25,000 German patients, taken by sticking thermometers under their arms. When doctors in the U.S. and Europe repeated the experiment in local...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized fever health inflammation Research Source Type: news
Abstract Background: Information on the effect of the recurrence pattern on survival for stage I lung cancer following stereotactic ablative radiotherapy (SABR) is limited.Materials and Methods: The recurrence pattern was analyzed for 100 consecutive stage I non-small-cell lung cancer patients treated with SABR using predominantly 12 Gy × 4. Recurrences were classified as local, regional lymph nodes and distant. Distant recurrences included recurrences in the lung and outside the chest. Single lung recurrences were named solitary, if no other location was involved. Kaplan-Meier survival estimates were...
Source: Acta Oncologica - Category: Cancer & Oncology Authors: Tags: Acta Oncol Source Type: research
Publication date: Available online 10 January 2020Source: Pathology - Research and PracticeAuthor(s): Jung Yong Hong, Ha Jung Kim, Kyung Kim, Joohyun Hong, Jung Eun Kim, Sun-ju Byeon, In-Kyoung Lee, Kyoung-Mee Kim, Moonhee Shim, Se Hoon Park, Joon Oh Park, Young Suk Park, Ho Yeong Lim, Seung Tae Kim, Jeeyun Lee, Won Ki KangAbstractThe potential anti-tumour role of statins has been reported in various cancer types, including gastric cancer (GC). However, there are no biomarkers to identify patients who may benefit most from this treatment. We tested the effects of statins on 8 GC cell lines. Genes differentially expressed i...
Source: Pathology Research and Practice - Category: Pathology Source Type: research
ConclusionMetformin and statins were not associated with BFFS or DFFS improvement in our analysis. However, the small number of patients treated with these drugs limits the reliability of the results and prospective studies are needed.
Source: Reports of Practical Oncology and Radiotherapy - Category: Cancer & Oncology Source Type: research
In this study, we investigated the anti-cancer effects of 3-hydroxy-3-methylglutaryl (HMG)-CoA reductase inhibitors and bisphosphonates in pancreatic cancer cell lines (SUIT-2 and MIA PaCa-2) which show poor responses to gemcitabine, established through long-term culture in nutrient-deprived or gemcitabine-containing media. Under the nutrient-deprived condition, IC50s for statins and bisphosphonates decreased and those for gemcitabine increased compared with those under normal conditions. In cells cultured long-term with gemcitabine, although IC50s for gemcitabine increased, those for statins and bisphosphonates either sli...
Source: Biological and Pharmaceutical Bulletin - Category: Drugs & Pharmacology Authors: Tags: Biol Pharm Bull Source Type: research
Title: AHA News: Statins May Do Double Duty on Heart Disease and CancerCategory: Health NewsCreated: 1/6/2020 12:00:00 AMLast Editorial Review: 1/7/2020 12:00:00 AM
Source: MedicineNet Cholesterol General - Category: Cardiology Source Type: news
ConclusionsOur analysis identified authors, countries, funding institutions, landmark contributions and high-impact-factor medical journals publishing RCTs. Over the last 50  years, publication production in leading medical journals has increased, with Western countries leading in research but with low- and middle-income countries showing very limited representation.
Source: Trials - Category: Research Source Type: clinical trials
Source: The Doctors Lounge - Oncology - Category: Cancer & Oncology Tags: Cardiology, Oncology, Pharmacy, News, Source Type: news
The objectives of this study were to evaluate the association of radioiodine treatment for hyperthyroidism with overall cancer and with specific cancer types. METHODS: This is a historical cohort study, using the Clalit healthcare database. Participants were all adults with a new diagnosis of hyperthyroidism in 2002 to 2015, newly treated with radioactive iodine, or with thionamides (propylthiouracil/thiamazole), excluding patients with previous malignancies. Age, sex, smoking history, body mass index, Clalit district, socioeconomic status, history of diabetes mellitus and of hypertension, use of aspirin and of statins...
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research
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