A pragmatic pilot phase II randomised controlled trial of prothrombin complex concentrates (PCC) versus fresh frozen plasma (FFP) in adult patients who are undergoing heart surgery (PROPHESY)

DiscussionThere have been no randomised controlled trials that have compared the safety and efficacy of FFP versus PCC in cardiac surgery patients who are bleeding. This pilot study will assess if individual components of a large trial are deliverable to assess the safety and efficacy of the two blood products in the future.Trial registrationEudraCT, 2018-003041-41; ClinicalTrials.gov,NCT03715348. Registered on 29 July 2018.
Source: Trials - Category: Research Source Type: clinical trials