CO poisoning. Routine ECG recorded before hyperbaric therapy....Are they related?

This patient was working on his truck in a garage without ventilation and the vehicle was running. He felt dizzy and lost consciousness. The next thing he remembers is waking up in the ambulance. He was last seen normal at 09:00 AM and was found down at 10:30 AM. He denied chest pain, abdominal pain, SOB or any other symptoms, though he did endorse chest pressure when asked specifically.He underwent a routine ECG prior to hyperbaric therapy for CO poisoning:Obvious Massive STEMI, Proximal LAD OcclusionHis CO level returned at 34%.Further h/o revealed that he had had a proximal LAD stent placed for a Non-Occlusion MI more than one year prior, and had been on clopidogrel for one year but was no longer on it.The cath lab was activated.The interventionalist told the patient that his ECG might be the result of CO poisoning only.I shook my head because this would be nearly impossible from CO poisoning only.  Itmight be possible with an extremely severely tight stenosis in the proximal LAD, but such a STEMI is never the result of CO poisoning alone.It was clear to me that this would be a proximal LAD occlusion, possibly at the site of the previous stent.It was decided to go the cath lab first, and then to the hyperbaric chamber for hyperbaric oxygen.Angiogram: Culprit Lesion (s): Thrombotic, in-stent occlusion of the proximal LAD24 hour echo:Regional wall motion abnormality-distal septum anterior and apex, akinetic.Regional wall motion abnormality-anterolateral, akinetic.Region...
Source: Dr. Smith's ECG Blog - Category: Cardiology Authors: Source Type: blogs

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Conclusion: In conclusion, AVMD is a genotypic and phenotypic heterogeneous disease. The genetic aetiology could not be explained by sequencing BEST1 and PRPH2 genes in the AVMD patients; however, the variant of PRPH2 could be a cause of predisposition relevant to the phenotype. PMID: 32942919 [PubMed - as supplied by publisher]
Source: Ophthalmic Genetics - Category: Opthalmology Tags: Ophthalmic Genet Source Type: research
Publication date: Available online 19 September 2020Source: Journal of Vascular and Interventional RadiologyAuthor(s): Jihoon Hong, Sang Yub Lee, Jung Guen Cha, Jae-Kwang Lim, Seung-Ick Cha, Young Woo Do
Source: Journal of Vascular and Interventional Radiology - Category: Radiology Source Type: research
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Source: Revue d Epidemiologie et de Sante Publique - Category: Epidemiology Tags: Rev Epidemiol Sante Publique Source Type: research
Authors: Chopra A, Bhat SG, Sivaraman K Abstract is an obligate, asaccharolytic, gram-negative bacteria commonly associated with increased periodontal and systemic inflammation. P. gingivalis is known to survive and persist within the host tissues as it modulates the entire ecosystem by either engineering its environment or modifying the host's immune response. It interacts with various host receptors and alters signaling pathways of inflammation, complement system, cell cycle, and apoptosis. P. gingivalis is even known to induce suicidal cell death of the host and other microbes in its vicinity with the emergence ...
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Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
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Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
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Source: Journal of Thoracic Disease - Category: Respiratory Medicine Tags: J Thorac Dis Source Type: research
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