Atypical secondary syphilis presentation in a patient with human immunodeficiency virus infection: a case report

ConclusionThis case emphasizes the importance of considering cutaneous secondary syphilis in the differential diagnosis of any inflammatory cutaneous disorder in individuals infected with human immunodeficiency virus.
Source: Journal of Medical Case Reports - Category: General Medicine Source Type: research

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Betsy Ambooken, Neelakandhan Asokan, KT Jisha, Lincy NinanIndian Journal of Sexually Transmitted Diseases and AIDS 2018 39(2):130-132Palmoplantar lesions of secondary syphilis are often termed “syphilis cornee.” A 32-year-old male presented with itchy lichenoid papules on both soles and left palm associated with grayish white papules on the buccal mucosa and glans penis. Initial clinical diagnosis of palmoplantar lichen planus with mucosal involvement was supported by the histopathological finding of interface dermatitis. However, more detailed history, serological tests of syphilis, and review of histopatholog...
Source: Indian Journal of Sexually Transmitted Diseases - Category: Infectious Diseases Authors: Source Type: research
In this report, we review the published literature on penile cellulitis and genital dermatitis artefacta. This case shows that military providers should always have psychiatric causes in their differential and not hesitate to ask about genital abnormalities. Recognition of underlying psychiatric etiology may play a key role in helping the patient get the care he or she needs. PMID: 30462252 [PubMed - as supplied by publisher]
Source: Military Medicine - Category: International Medicine & Public Health Tags: Mil Med Source Type: research
Discussion Hypopigmentation can be worrisome for many families because of cosmesis and the worry that “something is wrong.” The normal natural changes in skin-tone over the year due to different light exposure and wide variations within individuals is not something that many people are aware of. Post-inflammatory hypopigmentation is a common cause of hypopigmentation. Vitiligo is the most common cause of depigmentation. Vitiligo is an acquired, depigmenting disorder with typical lesions appearing as milky white macules with distinct margins that are not scaly. Hair (including eyebrows and eyelashes) can be dep...
Source: PediatricEducation.org - Category: Pediatrics Authors: Tags: Uncategorized Source Type: news
Publication date: March 2018Source: Dermatologica Sinica, Volume 36, Issue 1Author(s): Jee Hee Son, Sook Young Park, Bo Young Chung, Hye One Kim, Hee Jin Cho, Chun Wook ParkAbstractA 46-year-old woman presented with slightly itching, painless erythematous nodules on the face, neck, and genital area. Initial differential diagnoses included cutaneous lymphoma. We performed punch biopsy on her neck. In histopathology, interface dermatitis with some nodular infiltration of numerous neutrophils and plasma cells was observed, therefore, serologic tests for syphilis were performed. Owing to positive serologic test results and dra...
Source: Dermatologica Sinica - Category: Dermatology Source Type: research
Abstract Pityriasis rosea is a common self-limiting rash that usually starts with a herald patch on the trunk and progresses along the Langer lines to a generalized rash over the trunk and limbs. The diagnosis is based on clinical and physical examination findings. The herald patch is an erythematous lesion with an elevated border and depressed center. The generalized rash usually presents two weeks after the herald patch. Patients can develop general malaise, fatigue, nausea, headaches, joint pain, enlarged lymph nodes, fever, and sore throat before or during the course of the rash. The differential diagnosis inc...
Source: American Family Physician - Category: Primary Care Authors: Tags: Am Fam Physician Source Type: research
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Source: Journal of the European Academy of Dermatology and Venereology - Category: Dermatology Authors: Tags: Letter to Editor Source Type: research
Four o’clock on a Friday afternoon is an anxiety-inducing time to be running behind in clinic as patients and staff both begin to show signs of wanting to leave. After finishing with a particularly complicated case involving chronic pain with multiple spinal and abdominal surgeries, I rushed into the room of the patient scheduled for 3 p.m. frazzled. The patient was an elderly man, seated with arms folded, looking sternly down a knobby nose at me. I couldn’t help feeling guilty as he stared at me as if I’d done something to unforgivably wrong him. Trying to appear less disconcerted than I was, I started t...
Source: Kevin, M.D. - Medical Weblog - Category: General Medicine Authors: Tags: Education Infectious Disease Primary Care Source Type: blogs
Publication date: Available online 22 September 2017 Source:Dermatologica Sinica Author(s): Jee Hee Son, Sook Young Park, Bo Young Chung, Hye One Kim, Hee Jin Cho, Chun Wook Park A 46-year-old woman presented with slightly itching, painless erythematous nodules on the face, neck, and genital area. Initial differential diagnoses included cutaneous lymphoma. We performed punch biopsy on her neck. In histopathology, interface dermatitis with some nodular infiltration of numerous neutrophils and plasma cells was observed, therefore, serologic tests for syphilis were performed. Owing to positive serologic test results and dram...
Source: Dermatologica Sinica - Category: Dermatology Source Type: research
The chronic immune response induces the infiltration of the target organs with lymphocytes, which organize themselves into distinct T and B cell zones. This phenomenon has been termed tertiary lymphoid organ (TLO) formation and is often found in the mucosa as the mucosa-associated lymphoid tissue (MALT). By analogy, Streile in introduced a concept of skin-associated lymphoid tissue (SALT) based on the findings that the skin harbors T cells and dendritic cells (DCs). Although the existence of SALT had been controversial, we have confirmed sequential clustering of DCs and T cells at the dermal post-capillary venule in murine...
Source: Journal of Dermatological Science - Category: Dermatology Authors: Tags: P10-14[O3-12] Source Type: research
Conclusion This is the first study to identify and confirm these phenolic compounds in I. asarifolia leaves extract and to suggest that these compounds contribute to the anti-inflammatory activity in vivo, as reported by ethnomedicinal use of this plant. Through the different experimental models performed, we can conclude that the results obtained with the aqueous extract from I. asarifolia leaves support its popular use for the treatment of inflammatory disorders. Graphical abstract
Source: Journal of Ethnopharmacology - Category: Drugs & Pharmacology Source Type: research
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