The Effects of a Multimodal Approach for the Treatment of Primary Progressive Aphasia

Condition:   Primary Progressive Aphasia Interventions:   Device: Active tDCS;   Device: Placebo tDCS;   Behavioral: Language training;   Behavioral: Unstructured cognitive training Sponsors:   IRCCS Centro San Giovanni di Dio Fatebenefratelli;   Azienda Ospedaliera Spedali Civili di Brescia Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials

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Conclusion: While this is an unusual presentation of cerebral edema following DBS placement, ultimately, the outcome was good similar to other reported cases. Supportive care and corticosteroids remain the treatment of choice for this phenomenon. PMID: 33024597 [PubMed]
Source: Surgical Neurology International - Category: Neurosurgery Tags: Surg Neurol Int Source Type: research
Condition:   Aphasia Intervention:   Device: Rhythm-based speech therapy app (i.e., Speech Hero) Sponsors:   Ohio State University;   National Institute on Deafness and Other Communication Disorders (NIDCD) Suspended
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Conclusions 18F-PI-2620 PET might be a sensitive tool to detect cortical tau deposits in patients with Aβ+ AD and Aβ+ non-AD tauopathies. Furthermore, this study showed that “off-target” binding in the basal ganglia does not affect 18F-PI-2620.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Original Articles Source Type: research
This study highlights the impact of the size of deleted regions, as they may affect the clinical picture of patients with 16p11.2 microdeletion syndrome. Reported cases indicates the key role of the interdisciplinary approach in 16p11.2 microdeletion syndrome diagnostics, as the care of patients with this deletion is based on regular health assessment and adjustment of the nervous system develo pment therapy
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Genome variation profiling by SNP array Homo sapiens Source Type: research
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Source: Aphasiology - Category: Speech-Language Pathology Authors: Source Type: research
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Source: Aphasiology - Category: Speech-Language Pathology Authors: Source Type: research
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Source: Neuropsychological Rehabilitation - Category: Rehabilitation Authors: Source Type: research
Although the underlying pathophysiological mechanism of poststroke aphasia (PSA) is greatly concerned, it remains unclear. By coordinate ‐based (ALE) meta‐analysis, we found that the activation of the left superior frontal gyrus (SFG) and the parietal postcentral gyrus of PSA presented hypoactivation, while there was hyperactivation in the right cerebellar anterior lobe, fusiform gyrus, superior temporal gyrus (STG), superior par ietal lobule (SPL), and subgyral hippocampus. It is worth noting that the changed functional status of area in brain is more involved in right lobe. The future studies on rehabilitation should...
Source: Brain and Behavior - Category: Neurology Authors: Tags: ORIGINAL RESEARCH Source Type: research
A 65-year-old man presented with amnesia and aphasia for 1  year. Neurological examination revealed reduced strength and sensitivity in the right arm and leg. During hospital admission the patient also reported 38.5 °C fever, dyspnea and cough, associated with cervical lymph node enlargement. Brain magnetic resonance imaging demonstrated an abscess in the left parietal lobe (Fig. 1). Chest computed tomography (CT) showed diffuse ground-glass opacities and areas of reversed halo sign in both lungs, as well as expansive lesions in the adrenal glands and cervical lymph node enlargements (Fig.
Source: International Journal of Infectious Diseases - Category: Infectious Diseases Authors: Tags: Medical Imagery Source Type: research
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Source: Aphasiology - Category: Speech-Language Pathology Authors: Source Type: research
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