Mifepristone Antagonization With Progesterone to Prevent Medical Abortion: A Randomized Controlled Trial.

CONCLUSION: We could not estimate the efficacy of progesterone for mifepristone antagonization due to safety concerns when mifepristone is administered without subsequent prostaglandin analogue treatment. Patients in early pregnancy who use only mifepristone may be at high risk of significant hemorrhage. CLINICAL TRIAL REGISTRATION: ClinicalTrials.gov, NCT03774745. PMID: 31809439 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/31809439?dopt=Abstract

Source: Obstetrics and Gynecology - December 4, 2019 Category: OBGYN Authors: Creinin MD, Hou MY, Dalton L, Steward R, Chen MJ Tags: Obstet Gynecol Source Type: research