A Survey of Heads of Surgery and Residents on Accessibility and Employment in Liver Transplant Teams in Spain

ConclusionsThe generational turnover seems to be guaranteed according to liver transplant program directors. The new generations of surgeons generally opt for other areas of surgery other than transplantation. Studies with a greater number of responses are necessary to validate these results.ResumenIntroducciónEl acceso de los cirujanos a los equipos de trasplante hepático en España se realiza de manera heterogénea. El objetivo de este estudio ha sido cuantificar los recursos humanos de los equipos de trasplante españoles, la distribución de las diferentes tareas del trasplante entre los miembros del equipo, el mecanismo mediante el cual se adquieren las habilidades, la visión de sus líderes sobre su continuidad, así como las motivaciones de los residentes de cirugía general españoles para elegir el trasplante como su futura carrera profesional.MétodosSe elaboraron dos encuestas diferentes, para los jefes de equipo y para residentes, sobre número de personas, capacitación, reclutamiento, organización de tareas y motivación para trabajar en trasplantes. Los cuestionarios se enviaron por correo electrónico tanto a los directores de programa de trasplante como a los residentes de cirugía.ResultadosHay en promedio 8 cirujanos en cada unidad de trasplante. Más de 4 cirujanos realizan la hepatectomía en el 54,2% de los grupos, mientras que el i...
Source: Cirugia Espanola - Category: Surgery Source Type: research

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The increasing life expectancy of humans has led to a growing numbers of patients with chronic diseases and end-stage organ failure. Transplantation is an effective approach for the treatment of end-stage organ failure; however, the imbalance between organ supply and the demand for human organs is a bottleneck for clinical transplantation. Therefore, xenotransplantation might be a promising alternative approach to bridge the gap between the supply and demand of organs, tissues, and cells; however, immunological barriers are limiting factors in clinical xenotransplantation. Thanks to advances in gene-editing tools and immun...
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Publication date: Available online 22 January 2020Source: Best Practice &Research Clinical AnaesthesiologyAuthor(s): Evan E. Lebovitz, Anh Vinh T. Nguyen, Tetsuro SakaiAbstractCare for end-stage organ failure through transplant is one of the landmark accomplishments of the modern medicine. At the same time, organ transplant is a resource-intensive service that has been under increasing scrutiny in this era of cost containment. A detailed understanding of the economic implications of organ quality, recipient characteristics, and allocation policy is vital for the transplant professionals. Prior studies of kidney transpl...
Source: Best Practice and Research Clinical Anaesthesiology - Category: Anesthesiology Source Type: research
In conclusion APE-1 affects the expression of inflammatory factors and apoptosis in L-02 cells, so it may be a key gene in immune tolerance of liver transplantation. PMID: 31956225 [PubMed - in process]
Source: BioScience Trends - Category: Biomedical Science Tags: Biosci Trends Source Type: research
Variations in the vascular pattern of the celiac trunk and its branches should be considered while planning hepato-biliary surgery, including liver transplantation, multi-organ procurement and pancreatoduodenectomy, above all for locally advanced pancreatic cancer. The celiac trunk commonly comprises the left gastric artery, the common hepatic artery and the splenic artery. The superior mesenteric artery arises 1  cm below. In embryonic development, the abdominal visceral arteries arise from the primitive dorsal abdominal aorta through four roots: the left gastric artery, the hepatic artery, the splenic artery and the su...
Source: Digestive and Liver Disease - Category: Gastroenterology Authors: Tags: Image of the Month Source Type: research
AbstractPrimary biliary cholangitis is an uncommon cholestatic liver disease predominantly affecting middle-aged women. Left untreated, there is a high risk of progression to end-stage liver disease. Few treatment options exist. To date, ursodeoxycholic acid (UDCA) and obeticholic acid (OCA) are the only medical therapies approved for use, other than symptomatic treatments and liver transplantation, the latter of which is reserved for those developing complications of cirrhosis or with intractable pruritus. UDCA improves outcomes, but many patients do not adequately respond. OCA therapy may improve response, but long-term ...
Source: Journal of Gastroenterology - Category: Gastroenterology Source Type: research
AbstractBackgroundMalnutrition is common in patients with cirrhosis and is associated with poor outcomes after hepatic resection and liver transplantation. Transjugular intrahepatic portosystemic shunt (TIPS) is performed for complications of cirrhosis.AimTo assess the impact of malnutrition on TIPS outcomes.MethodsA retrospective analysis was performed using the Healthcare Cost and Utilization Project: National Inpatient Sample database for TIPS procedures from 2005 to 2014. The primary end point was in-hospital mortality. The association of specific malnutrition diagnostic codes and race –ethnicity on mortality was...
Source: Digestive Diseases and Sciences - Category: Gastroenterology Source Type: research
In conclusion, fibrotic liver clears necrotic areas and restores normal parenchyma faster than normal liver after I/R. This beneficial response appears to be directly related to the increased numbers of non-parenchymal cells, particularly phagocytic macrophages, in the fibrotic liver. PMID: 31961717 [PubMed - as supplied by publisher]
Source: Am J Physiol Gastroi... - Category: Gastroenterology Authors: Tags: Am J Physiol Gastrointest Liver Physiol Source Type: research
Sean Kelley, from Rochester, New York, lost 40 pounds to donate part of his liver to his one-year-old son, Sawyer, who suffers from Alagille syndrome, which scars and damages the liver.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
The J.P. Morgan Healthcare conference runs every year in San Francisco, a big draw for the biotech industry, and many organizations take the opportunity to host events at the same time. Among these, the SENS Research Foundation has for the past few years hosted a pitch day in which biotech companies in the longevity industry, largely startups, present to that portion of the Bay Area investor community interested in funding the treatment of aging as a medical condition. I was there to present on progress at Repair Biotechnologies, and took some notes on the other companies as they talked about their work. Kimera Labs ...
Source: Fight Aging! - Category: Research Authors: Tags: Investment Source Type: blogs
Authors: Tönshoff B Abstract Introduction: The goal of immunosuppressive therapy post-transplantation in pediatric renal transplant recipients is to prevent acute and chronic rejection while minimizing drug side effects. Most therapies alter immune response mechanisms but are not immunologically specific, and a careful balance is required to find the dose that prevents rejection of the graft, while minimizing the risks of over-immunosuppression leading to infection and cancer.Areas covered: This review article focuses on immunosuppressive therapy in pediatric renal transplant recipients, but many aspects can b...
Source: Expert Review of Clinical Immunology - Category: Allergy & Immunology Tags: Expert Rev Clin Immunol Source Type: research
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