Radioisotope synoviorthesis in the control of refractory synovitis in Castilla-La Mancha. A 10-year experience

Discussion and conclusionsIn patients with episodes of recurrent arthritis with associated joint effusion in one or two joints, refractory to systemic treatments, to local infiltrations with corticosteroids and for patients for whom other treatments may be contraindicated, we must consider the possibility of performing an isotope radiosinoviortesis, as it is a simple, safe technique with a success rate of more than 50%.ResumenNuestro hospital es el hospital de referencia en medicina nuclear para la realización de la sinoviortesis radioisotópica para toda Castilla La-Mancha.ObjetivoDescribir la experiencia en la realización de la sinoviortesis radioisotópica en las artritis refractarias a otros tratamientos en nuestro hospital.MetodologíaEstudio observacional, descriptivo y transversal protocolizado a través de la revisión de la base de datos de las sinoviortesis radioisotópicas realizadas entre 2007 y 2017. Se recopilaron datos clínicos previos (edad, sexo, proceso patológico, tratamientos previos, infiltración previa y articulación afectada) y evolutivos a los 6 meses tras administrar el isótopo. Se creó una base de datos Excel para un análisis de frecuencias con SPSS 21.ResultadosSe realizaron 30 radiosinoviortesis, siendo las enfermedades más frecuentes, por este orden: sinovitis villonodular pigmentada (40%), artritis reumatoide (23,3%), espondiloartritis (13,3%...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research

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ConclusionPN has variable distribution and high frequency in patients with RD; NQ+ increases the risk of presenting NCS+ for PN.
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
This study aims to discuss plasma and messenger RNA (mRNA) levels of interleukin (IL) ‐37 in rheumatoid arthritis (RA) patients and evaluate the potential of plasma IL‐37 as a biomarker for RA.MethodPlasma IL ‐37 levels and IL‐37 mRNA relative concentrations were measured by enzyme‐linked immunosorbent assay (ELISA) and quantitative reverse transcriptase‐polymerase chain reaction (RT‐PCR). We discussed the association of IL‐37 levels and clinical, laboratory parameters in RA patients in a tra ining cohort. Plasma IL‐37 levels were tested for discriminatory capacity by receiver operating characteristic (RO...
Source: International Journal of Rheumatic Diseases - Category: Rheumatology Authors: Tags: ORIGINAL ARTICLE Source Type: research
ConclusionsSociodemographic and lifestyle changes over the last 16 years justify EPISER 2016. This study will provide current data about the prevalences of RA, AS, PsA, SLE, SS, osteoarthritis, fibromyalgia, gout and clinical osteoporotic fracture. The results will allow comparisons with studies from other countries and EPISER 2000.ResumenObjetivosDescribir la metodología del estudio de prevalencia de las enfermedades reumáticas en la población adulta en España, EPISER 2016, así como sus fortalezas y limitaciones. El objetivo del proyecto es estimar la prevalencia de artritis reumatoide (...
Source: Reumatologia Clinica - Category: Rheumatology Source Type: research
Abstract Previous studies have indicated that interleukin-38 (IL-38) is involved in rheumatoid arthritis (RA). The present study aims to assess plasma levels of IL-38 in RA and discuss the potential of IL-38 as a biomarker for RA. Protein concentrations of IL-38 were examined by enzyme-linked immunosorbent assay, and the mRNA level of IL-38 was tested by quantitative real-time polymerase chain reaction. Plasma IL-38 was first compared in a training cohort, including 130 RA patients and 53 healthy controls, given the optimal cutoff. Then, we validated the levels of IL-38 in a further cohort of 519 patients, includi...
Source: International Immunopharmacology - Category: Allergy & Immunology Authors: Tags: Int Immunopharmacol Source Type: research
(Bentham Science Publishers) The text combines comprehensive and systematic information about the diseases with a collection of diagnostic images. The key feature of the book is the systemic approach towards medical diagnosis in cases based on radiographic imaging. Topics covered in the book include also include osteoarthritis, lupus, myositis, vasculitis, juvenile arthritis, gout, systemic sclerosis, adult onset Still's disease, Beh ç et's disease and so on. Chapters have been contributed by experts in rheumatology.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
Authors: Castrejón I, Chua JR, Pincus T Abstract A physician global assessment of patient status (DOCGL) was designed initially to quantitate inflammatory activity in rheumatoid arthritis (RA) clinical trials, in which patients are selected for high levels of activity. However, in patients seen in routine care with various diagnoses, and even in some RA patients selected for clinical trials, DOCGL also may be affected by joint damage and/or patient distress. To clarify DOCGL on a 0-10 visual analogue scale (VAS), 3 additional 0-10 VAS have been developed to record physician estimates of inflammation (DOCINF)...
Source: Clinical and Experimental Rheumatology - Category: Rheumatology Tags: Clin Exp Rheumatol Source Type: research
Conclusions Although rheumatic diseases are noted at a high rate in north Cyprus, there is no associated HCV infection.
Source: The Egyptian Rheumatologist - Category: Rheumatology Source Type: research
On March 7, the Centers for Disease Control and Prevention (CDC) issued new data on the prevalence of arthritis in the USA. More than 54 million adults (23%) in the USA report arthritis diagnosed by a doctor, and almost 60% are of working age (18 –64 years old). 24 million adults with arthritis report that the disease limits their daily activities, which represents an increase of about 20% since 2002. Most have osteoarthritis, but rheumatoid arthritis, gout, lupus, and fibromyalgia are other common diagnoses in the report.
Source: LANCET - Category: Journals (General) Authors: Tags: Editorial Source Type: research
AbstractWe performed a systematic review designed to characterize clinical phenotypes and outcomes in Indigenous populations with rheumatic disease to enhance the understanding of how rheumatic disease presents in Indigenous populations and allow for better projection of the healthcare needs of the communities affected. A systematic search was performed in medical (Medline, EMBASE, CINAHL), Indigenous and conference abstract databases (to June 2015). Search terms for Indigenous populations were combined with terms for inflammatory arthritis conditions, connective tissue disorders, crystal arthritis and osteoarthritis. Stud...
Source: Rheumatology International - Category: Rheumatology Source Type: research
SPECIAL FROM Next Avenue Whether it came on suddenly when you were playing tennis or more gradually over many years, knee pain can keep you from doing even the most basic of activities. At the very least, it can limit your ability to move as easily or quickly, or sit in one place for an extended time.   Arthritis is the most common cause of knee pain for older adults, said Dr. Julie Switzer, an orthopedic surgeon at Regions Hospital in St. Paul, Minn. Arthritis comes in three main forms, she said: osteoarthritis, inflammatory arthritis and post-traumatic arthritis. We’ll examine these types, as well as other ...
Source: Healthy Living - The Huffington Post - Category: Consumer Health News Source Type: news
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