Optimization of the accelerated partial breast brachytherapy fractionation considering radiation effect on planning target and organs at risk

The same fractionation scheme of accelerated partial breast irradiation (APBI) with brachytherapy is usually applied to APBI patients without considering the radiaton effect on the planning target and organs at risk (OARs) for an individual patient. The purpose of this study is to report the results of optimization of the fractionation scheme by evaluating the radiation effect on target and OARs with a modified linear-quadratic model, universal survival curve (USC), based on dose-volume histograms (DVHs).
Source: Medical Dosimetry - Category: Radiology Authors: Source Type: research