Type 1 diabetes linked PTPN22 gene polymorphism is associated with the frequency of circulating regulatory T cells.

In conclusion, our analysis implicates the autoimmune PTPN22 rs2476601 risk allele A in controlling the frequency of Tregs in human peripheral blood. This article is protected by copyright. All rights reserved.
PMID: 31808541 [PubMed - as supplied by publisher]

Source: European Journal of Immunology - December 5, 2019 Category: Allergy & Immunology Authors: Milla V, Mahfuz GA, Tyyne V, Emmi-Leena I, Ilse E, Jorma T, Mikael K, Riitta V, Jorma I, Johanna L, Tuure K Tags: Eur J Immunol Source Type: research