TGM3 promotes epithelial –mesenchymal transition and hepatocellular carcinogenesis and predicts poor prognosis for patients after curative resection

Prognosis of hepatocellular carcinoma (HCC) remains poor despite significant recent improvement in therapy. Recent studies have reported that transglutaminase 3 (TGM3) plays an important role in several human cancer types. However, the role of TGM3 in HCC have not been previously elucidated.

Source: Digestive and Liver Disease - December 6, 2019 Category: Gastroenterology Authors: Jin-Wu Hu, Zhang-fu Yang, Jia Li, Bo Hu, Chu-Bin Luo, Kai Zhu, Zhi Dai, Jia-Bin Cai, Hao Zhan, Zhi-Qiang Hu, Jie Hu, Ya Cao, Shuang-Jian Qiu, Jian Zhou, Jia Fan, Xiao-Wu Huang Tags: Oncology Source Type: research