Detection of Unusual Peritoneal Metastases of Prostate Cancer With 68Ga–Prostate-Specific Membrane Antigen PET/CT

We present a case of a 68-year-old man with disseminated peritoneal metastases and abdominal metastatic lymph nodes of PC, demonstrated in 68Ga-PSMA PET/CT with intense PSMA uptake.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research

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Robot-assisted laparoscopic radical prostatectomy is one of the treatment options for localized prostate cancer, with an excellent disease control rate. However, these patients can experience late disease recurrence with metastatic dissemination. Peritoneal metastases are an uncommon recurrence site. Here, we discuss 3 cases of peritoneal metastases following robot-assisted laparoscopic radical prostatectomy and the mechanisms of peritoneal invasion. Through a literature review and our case reports, we postulate the existence of 2 distinct mechanisms of peritoneal invasion: one being iatrogenic, following a laparoscopic su...
Source: Urology - Category: Urology & Nephrology Authors: Tags: Review Article Source Type: research
Robot-assisted laparoscopic radical prostatectomy (RALRP) is one of the treatment options for localized prostate cancer, with an excellent disease control rate. However, these patients can experience late disease recurrence with metastatic dissemination. Peritoneal metastases are an uncommon recurrence site. Here, we discuss three cases of peritoneal metastases following RALRP and the mechanisms of peritoneal invasion. Through a literature review and our case reports, we postulate the existence of two distinct mechanisms of peritoneal invasion: one being iatrogenic, following a laparoscopic surgery with a well differentiat...
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
Rationale: The problem of the coexistence of gastrointestinal stromal tumor (GIST) with other neoplasms is complex, and carcinomas of prostate is one of the common types of GIST-associated cancers. Doubling time of GIST is about 3.9 months for high-risk GIST, and the treatment paradigm for GIST has required the integration of surgery and molecular therapy. Patient concerns: A 70-year-old man with postoperative history of prostate cancer experienced fast-growing malignant jejunal GIST with multiple peritoneal metastases within 1 year. Diagnoses: Enhanced computed tomography (CT) detected a neoplasm of small intestin...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
UCLA scientists have developed a new method to quickly screen hundreds of drugs in order to identify treatments that can target specific tumors.The approach could help scientists understand how a person ’s tumor would respond to a certain drug or drug combination, and it could help guide treatment decisions for people with rare and hard-to-treat cancers. Apaper detailing the new technique was published in Communications Biology.“We always focus on how we need new and better drugs to treat cancer,” said Alice Soragni, the senior author of the study and a scientist at the UCLA Jonsson Comprehensive Can...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
ConclusionsAlthough an overall deficit in cancer was observed, there were notable exceptions, including newly observed excesses for AML, thyroid, testicular, and peritoneal cancers. Furthermore, endotoxin exposure may, in part, account for observed lung cancer incidence deficits. Cancer incidence patterns in the AHS suggest farm exposures ’ relevance to cancer etiology.
Source: Cancer Causes and Control - Category: Cancer & Oncology Source Type: research
We report a case of urachus metastases showed on 68Ga-PSMA PET/CT performed for biochemical recurrence with a very low PSA level at 0.50 ng/mL.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Publication date: Available online 12 August 2018Source: Urology Case ReportsAuthor(s): Félix Couture, Joshua Chin, Jaron Chong, Simon Tanguay
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
We report a case of 68Ga-PSMA PET/MR–positive peritoneal metastasis as site of primary relapse after definitive PCa treatment in a 58-year-old man with a prostate-specific antigen of 30 ng/mL at time of the study. Exploratory laparoscopy and subsequent histopathologic examination confirmed nonascitic peritoneal PCa carcinomatosis.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Conclusion: F-18 FDG PET/CT has high diagnostic accuracy for detection of residual/recurrent disease in stomach cancer after treatment. Metachronous primary malignancy may also be incidentally detected. Research Support: N A
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: GI-Non-colorectal Source Type: research
This article summarizes the milestones in the development of niraparib leading to its first global approval for the maintenance treatment of adult patients with recurrent epithelial ovarian, fallopian tube or primary peritoneal cancer.
Source: Drugs - Category: Drugs & Pharmacology Source Type: research
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