Mixed States: Beyond Depression and Mania

Publication date: Available online 6 December 2019Source: Psychiatric Clinics of North AmericaAuthor(s): Gabriele Sani, Alan C. Swann
Source: Psychiatric Clinics of North America - Category: Psychiatry Source Type: research

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Authors: Barton BB, Segger F, Fischer K, Obermeier M, Musil R Abstract Introduction: Antipsychotic-induced weight-gain (AIWG) is a very important, yet often neglected side-effect in the treatment with first and second generation antipsychotics. AIWG can increase the risk of developing metabolic syndrome, diabetes and cardiovascular disease. Meta-analyses mostly concentrate on AIWG in schizophrenic and bipolar patients, even though antipsychotics are prescribed off-label across many other diagnostic groups (e.g. anxiety disorders, depression, autistic disorder).Areas covered: Pub Med and Web of Science were systemat...
Source: Expert Opinion on Drug Safety - Category: Drugs & Pharmacology Tags: Expert Opin Drug Saf Source Type: research
Publication date: Available online 18 January 2020Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Shaoqiang Han, Qian Cui, Xiao Wang, Yuyan Chen, Di Li, Liang Li, Xiaonan Guo, Yun-Shuang Fan, Jing Guo, Wei Sheng, Feng-Mei Lu, Zongling He, Huafu ChenAbstractDuring depressive episode, bipolar disorder (BD) patients share indistinguishable depression symptoms with major depressive disorder (MDD).However, whether neural correlates underlying the anhedonia, a core feature of depression, is different between BD and MDD remains unknown. To explore neural correlates underlying the anhedonia in BD a...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
AbstractPurpose of ReviewBipolar disorder has the highest rate of suicide of all psychiatric conditions and is approximately 20 –30 times that of the general population. The purpose of this review is to discuss findings relevant to bipolar disorder and suicide.Recent FindingsRisk factors include male gender, living alone, divorced, no children, Caucasian, younger age (  75 years), unemployment, and a personal history of suicide attempt and family history of suicide attempt or suicide completion, as well as predominant depressive polarity. Suicide is associated with the depressed or mixed subtypes, not man...
Source: Current Psychiatry Reports - Category: Psychiatry Source Type: research
In this study, patients didn’t need a smartphone[PM1] . It could be simple and low tech on the patient end, and high tech on the backend.”Researchers hope that artificial intelligence that can analyze data collected from apps such as My Coach Connect will enable more proactive and personalized care for individuals. The application, for example, may help improve treatment by intervening early when someone is experiencing more symptoms.“Artificial intelligence allowed us to illuminate the various clinically meaningful dimensions of language use and vocal patterns of the patients over time and pers...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
 Touch is a powerful thing. From the time we’re born, and throughout our lives, humans need touch to thrive and develop properly. Sadly, many people in our culture experience a profound lack of caring and respectful platonic touch. Today’s guest, Rev. Edie Weinstein, has a remedy for this. She is the founder of Hug Mobsters Armed With Love, which offers FREE HUGS events for the public. Tune in to discover how Edie got started in the hugging “business,” the ins and outs of giving free hugs in public, and how she manages to gently navigate our culture’s understandable wariness of inappropria...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: General Inspiration & Hope Interview Mental Health and Wellness Podcast The Psych Central Show Source Type: blogs
ConclusionPsychotropic medication non-adherence was high. It was influenced by various factors operating at different levels. Therefore, comprehensive intervention strategies should be designed to address factors associated with psychotropic medication non-adherence.Systematic review registrationPROSPERO CRD42017067436
Source: Systematic Reviews - Category: International Medicine & Public Health Source Type: research
Astudy appearing today inJAMA Psychiatry found that fewer than 7% of patients with psychiatric disorders in Sweden had either been subjected to violence severe enough to require specialist medical treatment or had perpetrated violence.Amir Sariaslan, Ph.D., of the University of Oxford and colleagues identified 250,419 individuals from Sweden ’s National Patient Register who were born between 1973 and 1993 and had been diagnosed psychiatric disorders. Psychiatric disorders included anxiety disorders, depression, bipolar disorder, schizophrenia, personality disorders, alcohol use disorder, and drug use disorder. The pa...
Source: Psychiatr News - Category: Psychiatry Tags: Amir Sariaslan anxiety bipolar disorder depression JAMA Psychiatry Paul Appelbaum personality disorders schizophrenia substance use disorder violence Source Type: research
This study is an important first step in trying to decrease the severity of bipolar disorder early on for children,” said Dr. Christopher Schneck, an associate professor of psychiatry at the University of Colorado Anschutz Medical Campus and a co-author of the study. “Efforts at home and in health care settings, like providing skill training for families, can make a big difference in a child’s suffering.”
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
AbstractPurpose of ReviewThis paper aims to review current available treatment options and to consider future directions in the treatment of bipolar depression.Recent FindingsThere are a limited number of established treatments that have demonstrated varied efficacy in acute bipolar depression including modern antipsychotics (quetiapine, lurasidone, olanzapine ± fluoxetine and recently cariprazine) and mood stabilisers (lamotrigine and valproate). Lithium has a role in protecting against depressive relapses and suicide. Alternative and experimental treatments including pramipexole, modafinil/armodafinil, omega-3 fat...
Source: Current Behavioral Neuroscience Reports - Category: Neuroscience Source Type: research
DiscussionCACNA1C rs11615998 was associated with psychotic symptoms (C-allele carriers have decreased psychotic-risk) independently from the diagnosis, in line with the evidence of a cross disorder effect of many risk variants. This gene was previously associated with SCZ and cross-disorder liability to psychiatric disorders. Our findings confirmed that deep phenotyping is pivotal to clarify the role of genetic variants on symptoms patterns.
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
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