Structural, morphometric and immunohistochemical study of the rabbit accessory olfactory bulb.
Structural, morphometric and immunohistochemical study of the rabbit accessory olfactory bulb.
Brain Struct Funct. 2019 Dec 04;:
Authors: Villamayor PR, Cifuentes JM, Quintela L, Barcia R, Sanchez-Quinteiro P
Abstract
The accessory olfactory bulb (AOB) is the first neural integrative centre of the vomeronasal system (VNS), which is associated primarily with the detection of semiochemicals. Although the rabbit is used as a model for the study of chemocommunication, these studies are hampered by the lack of knowledge regarding the topography, lamination, and neurochemical properties of the rabbit AOB. To fill this gap, we have employed histological stainings: lectin labelling with Ulex europaeus (UEA-I), Bandeiraea simplicifolia (BSI-B4), and Lycopersicon esculentum (LEA) agglutinins, and a range of immunohistochemical markers. Anti-G proteins Gαi2/Gαo, not previously studied in the rabbit AOB, are expressed following an antero-posterior zonal pattern. This places Lagomorpha among the small groups of mammals that conserve a double-path vomeronasal reception. Antibodies against olfactory marker protein (OMP), growth-associated protein-43 (GAP-43), glutaminase (GLS), microtubule-associated protein-2 (MAP-2), glial fibrillary-acidic protein (GFAP), calbindin (CB), and calretinin (CR) characterise the strata and the principal components of the BOA, demonstrating several singular features of the rabbit AOB. This diversity is accentuated b...
Source: Brain Structure and Function - Category: Neuroscience Authors: Villamayor PR, Cifuentes JM, Quintela L, Barcia R, Sanchez-Quinteiro P Tags: Brain Struct Funct Source Type: research