GSE141554 Spleen transcriptomes during behavioural fever in Salmo salar

Contributors : Sebastian Boltana ; Andrea AguilarSeries Type : Expression profiling by high throughput sequencingOrganism : Salmo salarThe transcriptomic analysis was evaluated using RNA-seq of salmon challenged with the birnavirus IPNv under two different thermal conditions: (a) constant temperature (mean temperature 15 ± 0.9 ºC, “No-Fever”) and (b) temperature gradient (mean temperature 15 ± 7.4 ºC, “Fever”). In parallel, fish in another tank were treated by adding 100 ml virus free cell culture supernatant to the water (mean temperature 15 ± 7.4 ºC, "mock-infected"). We identified a specific transcr iptomic signature for each group in the RNA-seq data and identifying a set of key components that control inflammatory modulation during behavioural fever upon viral infection in mobile ectotherms.

Source: GEO: Gene Expression Omnibus - December 7, 2019 Category: Genetics & Stem Cells Tags: Expression profiling by high throughput sequencing Salmo salar Source Type: research