Susceptibility patterns in Neisseria gonorrhoeae in Nuuk, Greenland, 2015-2018: a short communication.

In conclusion no ceftriaxone resistance has been found in Nuuk to date. Continued easy access to diagnostics and treatment combined with increased and more systematic surveillance of antimicrobial susceptibility in Nuuk is recommended. Further, it is advisable to investigate the possibilities for intermittent sampling in Greenland outside of Nuuk, if obstacles in relation to sending sampling material to Nuuk can be bypassed. PMID: 31809690 [PubMed - in process]
Source: International Journal of Circumpolar Health - Category: International Medicine & Public Health Tags: Int J Circumpolar Health Source Type: research

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This study reviewed existing work on specific DNA sequences and their link to resistance in Neisseria gonorrhoeae, and evaluated these sequences to identify accurate markers of resistance for two treatments of gonorrhoea. If incorporated into diagnostic tests, these could allow diagnosis of the infection and its resistance pattern together, improving treatment efficacy and preventing further spread of resistance.
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In conclusion, the cross-resistance with azithromycin indicates that cethromycin may not be considered for empirical first-line monotherapy of gonorrhoea. However, cethromycin might be valuable in combination antimicrobial therapy and for second-line therapy e.g. for cases with ceftriaxone resistance or allergy. PMID: 31106713 [PubMed - as supplied by publisher]
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Source: The Lancet - Category: General Medicine Source Type: research
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