What's new in obstetric antiphospholipid syndrome.

What's new in obstetric antiphospholipid syndrome. Hematology Am Soc Hematol Educ Program. 2019 Dec 06;2019(1):421-425 Authors: Branch DW Abstract Antiphospholipid syndrome (APS) is a rare systemic autoimmune disease, the obstetric features of which include recurrent early miscarriage, fetal death at or beyond 10 weeks of gestation, and early delivery for severe preeclampsia or placental insufficiency. Controversies regarding the specificity of these obstetric clinical features, as well as the laboratory diagnostic criteria, are the subject of current debate and reanalysis. Clinical and laboratory features can be used to stratify women with APS in terms of risk of adverse second and third trimester pregnancy outcomes. Numerous "treatments" have been used in high-risk and refractory patients, but rigorously designed clinical trials are needed. APS is a rare disease that requires innovative investigative approaches to provide credible results. PMID: 31808896 [PubMed - in process]
Source: Hematology ASH Education Program - Category: Hematology Tags: Hematology Am Soc Hematol Educ Program Source Type: research

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How bad of an idea is it to be pregnant with adequate lead coverage during early months of pregnancy? I had a fellow resident who was pregnant who changed her rotations around to avoid any exposure, however it's my understanding that overall the exposure with adequate coverage is ultimately fine. I know most of you are men - not sure if there are any female pain docs who could chime in? Sigh.
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