Role of Immunohistochemistry to Distinguish Grade 3 Endometrioid Carcinoma and Uterine Serous Carcinoma

Conclusions: The most appropriate IHC panel to differentiate endometrioid and serous endometrial carcinomas includes ER, PR, IMP3, p53, and p16.
Source: Applied Immunohistochemistry and Molecular Morphology - Category: Chemistry Tags: Research Articles Source Type: research

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ConclusionThe results suggest that weight perception explains part of the relationship between physical activity and life satisfaction in adolescents and that these effects vary as a function of age and sex.Graphical abstract
Source: Journal of Sport and Health Science - Category: Sports Medicine Source Type: research
In this study, we examined 1,182 subjects (658 men and 524 women, 62.3 ± 11.7 years on average) who underwent voluntary health check-ups and sought to determine the optimal cut-off value of WC for predicting carotid IMT thickness. Receiver operating characteristic curve analysis of WC was utilized to predict high carotid IMT (defined as carotid IMT ≥ 1.1 mm). We determined that the appropriate WC cut-off value was a WC ≥ 79 cm for men and women. There was a statistically significant difference in the prevalence of high carotid IMT between WC ≥ 79 cm and WC
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
Authors: Wu CC, Chang CS, Hsu CC, Wang CP, Tsai IT, Lu YC, Houng JY, Chang CC, Chung FM, Lee YJ, Hung WC Abstract Low-circulating levels of adiponectin (ADPN) are associated with obesity, diabetes mellitus, and coronary artery disease. On the contrary, some studies have demonstrated a link between relatively high levels of plasma ADPN and heart failure, atrial fibrillation, and adverse outcome. However, little is known about the relationship between ADPN level and prolonged QT interval. The aim of this study was to investigate the association between plasma ADPN levels and prolonged QT interval in patients with sta...
Source: International Heart Journal - Category: Cardiology Tags: Int Heart J Source Type: research
ConclusionsThe G.R.O.S. management style seems to be an interesting and effective alternative to slimming diets. However, this study presented a number of limitations, including the sample size, nonrandomization of subjects in groups, and non-standardization of care.RésuméIntroductionLes recommandations internationales destinées aux personnes souffrant d’obésité ou de surpoids basées sur des conseils nutritionnels qualitatifs et/ou quantitatifs ne sont pas efficaces sur le long terme. En revanche, l’alimentation intuitive, qui consiste à manger naturellement en f...
Source: European Review of Applied Psychology - Category: Psychiatry & Psychology Source Type: research
CONCLUSION: The T-shaped linear-stapled cervical esophagogastric anastomosis is efficient, reliable, easy to perform, and associated with lower postoperative complication rate. PMID: 31955641 [PubMed - as supplied by publisher]
Source: Tumori - Category: Cancer & Oncology Tags: Tumori Source Type: research
Publication date: Available online 22 January 2020Source: Nutrition, Metabolism and Cardiovascular DiseasesAuthor(s): Giuseppe De Luca, Monica Verdoia, Stefano Savonitto, Luca A. Ferri, Luigi Piatti, Daniele Grosseto, Nuccia Morici, Irene Bossi, Paolo Sganzerla, Giovanni Tortorella, Michele Cacucci, Maurizio Ferrario, Ernesto Murena, Girolamo Sibilio, Stefano Tondi, Anna Toso, Sergio Bongioanni, Amelia Ravera, Elena Corrada, Matteo MarianiAbstractBackgroundElderly patients are at increased risk of hemorrhagic and thrombotic complications after an acute coronary syndrome (ACS). Frailty, comorbilities and low body weight hav...
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research
TC-325 (Hemospray, Cook Medical, Winston-Salem, North Carolina, USA) is a propriety mineral blend powder developed for the purpose of endoscopic hemostasis. The powder was originally approved for use in stopping bleeding from external wounds in both civilian and military injuries. In 2011, our group reported its first endoscopic application in patients with actively bleeding peptic ulcers.1 The powder was sprayed onto the bleeding vessel with  the use of a pressurized carbon dioxide canister. In 19 of 20 patients, hemostasis was achieved.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Original article Source Type: research
We read with great interest the original article “Hemostatic spray powder TC-325 for GI bleeding in a nationwide study: survival and predictors of failure via competing risks analysis” by Rodríguez et al.1 In this retrospective study, patients were treated with TC-325, an inorganic hemostatic powder (Hemospray). The authors concluded the s afety and effectivity of TC-325 for intraprocedural hemostasis regardless of the cause or site of bleeding and its use as rescue therapy.
Source: Gastrointestinal Endoscopy - Category: Gastroenterology Authors: Tags: Letter to the Editor Source Type: research
ConclusionWe identify iRhom2 as a key regulator that promotes obesity-associated metabolic disorders. Loss of iRhom2 from macrophages in adipose tissues may indirectly restrain inflammation and insulin resistance via blocking crosslink between macrophages and adipocytes. Hence, iRhom2 may be a therapeutic target for obesity-induced metabolic dysfunction.Graphical abstract
Source: Molecular Metabolism - Category: Endocrinology Source Type: research
This study investigates the effects of QD on murine dextran sulfate sodium salt-induced colitis. Oral administration of QD protected the animals from colitis as manifested by weight loss, diarrhea, and rectal bleeding. QD was distinguishingly more effective than 5-aminosalicylate. Focused microarray analysis of genes expressed in the distal colon suggested that QD influences the inflammatory pathway. Anti-inflammatory activity of QD was confirmed by the suppression of nitric oxide (NO) production in response to interleukin-1β in cultured hepatocytes. Some of the constituents in QD, such as tryptanthrin (TRYP) and indi...
Source: Journal of Pharmacological Sciences - Category: Drugs & Pharmacology Source Type: research
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