The ASPIRE Trial - Aiming for Safe Pregnancies by Reducing Malaria and Infections of the Reproductive Tract

Conditions:   Pregnancy Malaria;   Bacterial Vaginoses;   Trichomonas Vaginitis Interventions:   Drug: IPTp-sulphadoxine-pyrimethamine plus metronidazole;   Drug: IPTp-dihydroartemisinin-piperaquine plus metronidazole;   Drug: IPTp-sulphadoxine-pyrimethamine Sponsor:   London School of Hygiene and Tropical Medicine Not yet recruiting
Source: - Category: Research Source Type: clinical trials

Related Links:

[East African] The Global Fund, the body that finances the world's HIV, tuberculosis (TB) and malaria programmes, has given Kenya Ksh42 billion ($420 million) to cover the intervening years to 2024.
Source: AllAfrica News: Health and Medicine - Category: African Health Source Type: news
Date: Tuesday, 01 28, 2020; Speaker: Ricardo T. Gazzinelli, Professor, University of Massachusetts Medical School; 12735 Twinbrook Pkwy; 2nd Floor Conference Room
Source: NIH Calendar of Events - Category: American Health Source Type: events
There was nothing quite like the slang used in the early days of the space program. Saying something was “OK” would not do when you could say “A-OK” instead. Saying, “Let’s get moving,” when you’ve been sealed in your spacecraft for hours waiting to launch while Mission Control sorts out technical glitches, was weak tea compared to the “Light this candle!” as an exasperated Al Shepard barked in 1961. And then, too, there was “screw the pooch.” A cleaned-up version of a decidedly coarser term, it meant, in the pilot’s argot, to crash your jet or l...
Source: TIME: Science - Category: Science Authors: Tags: Uncategorized climate change newsletter Space Source Type: news
Source: Human Vaccines and Immunotherapeutics - Category: Allergy & Immunology Authors: Source Type: research
Conclusion: This paper features an autonomous, portable, 1-min analysis time, and low-cost per test device, without the need for samples, centrifugation, allowing the use of whole blood. Significance: The presented device is a step ahead for meeting the growing clinical demands for reliable, rapid, portable, and quantitative malaria diagnosis.
Source: IEEE Transactions on Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Netter : Hepatitis B remains one of the major global health problems more than 40 years after the identification of human hepatitis B virus (HBV) as the causative agent. A critical turning point in combating this virus was the development of a preventative vaccine composed of the HBV surface (envelope) protein (HBsAg) to reduce the risk of new infections. The isolation of HBsAg sub-viral particles (SVPs) from the blood of asymptomatic HBV carriers as antigens for the first-generation vaccines, followed by the development of recombinant HBsAg SVPs produced in yeast as the antigenic components of the second-generation va...
Source: Viruses - Category: Virology Authors: Tags: Review Source Type: research
Despite a 30% decline in mortality since 2000, malaria still affected 219 million subjects and caused 435,000 deaths in 2017. Red blood cells (RBC) host Plasmodium parasites that cause malaria, of which Plasmodium falciparum is the most pathogenic. The deformability of RBC is markedly modified by invasion and development of P. falciparum. Surface membrane area is potentially impacted by parasite entry and development, the cytoskeleton is modified by parasite proteins and cytosol viscosity is altered by parasite metabolism. RBC hosting mature parasites (second half of the asexual erythrocytic cycle) are abnormally stiff but...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Not in person, as both are rather historical, but when in Paris, I encountered:Dr Alphonse LaveranandDr Paul GachetDr Laveran has a square named after him, adjacent to the Ecole de Val de Grace, a school of military medicine, where he worked after serving in the army as a physician, and where his father had held the same post.   Paris is good at telling you who a street is named after, so the street sign tells you he was the first French winner of theNobel Prize for Medicine or Physiology.  He won it for identifying both malaria and sleeping sickness as caused by parasites.Dr Gachet has aportrait in the...
Source: Browsing - Category: Databases & Libraries Source Type: blogs
[Daily Trust] Abuja -Prince Ned Nwoko just returned from a historic expedition to the world's coldest continent, Antarctica where he went to formally flag off his ambitious project to eradicate malaria from Africa.
Source: AllAfrica News: Malaria - Category: Infectious Diseases Source Type: news
ConclusionThe present study revealed that oral administration of CM extract for 28 days, at dosage up to 1000 mg/kg did not induce toxicological damage in rats. From acute toxicity study, the median lethal dose (LD50) of the extract was estimated to be more than 5000 mg/kg.Graphical abstract
Source: Toxicology Reports - Category: Toxicology Source Type: research
More News: Malaria | Metronidazole | Research