Initial Psychometric Testing of the Knowledge About Atrial Fibrillation and Self-Management Survey
We report results of initial psychometric testing of the Knowledge about Atrial Fibrillation and Self-Management (KAFSM) survey. Methods Participants (N = 383), from midwest and southeast medical centers, completed the KAFSM survey. Content validity was evaluated by expert review. Construct validity was evaluated using the Pearson correlation procedure for convergent validity with the Knowledge about Atrial Fibrillation test and independent t test for known groups. Factor analysis using principal axis factoring was performed with a tetrachoric matrix. The Kuder-Richardson procedure was used to determine internal consistency reliability. Results A content validity index of 0.86 resulted from expert review. A positive (r = 0.60) correlation between the KAFSM survey and Knowledge about Atrial Fibrillation test demonstrated convergent validity. Higher KAFSM scores (difference, 3.28; t = 6.44, P
Authors: Mujer MTP, Rai MP, Atti V, Dimaandal IL, Chan AS, Shrotriya S, Gundabolu K, Dhakal P Abstract Non-vitamin K antagonist oral anticoagulants (NOACs) include thrombin inhibitor dabigatran and coagulation factor Xa inhibitors rivaroxaban, apixaban, edoxaban, and betrixaban. NOACs have several benefits over warfarin, including faster time to the achieve effect, rapid onset of action, fewer documented food and drug interactions, lack of need for routine INR monitoring, and improved patient satisfaction. Local hemostatic measures, supportive care, and withholding the next NOAC dose are usually sufficient to achie...
Authors: Bazarbashi N, Miller M Abstract INTRODUCTION: Icosapent Ethyl (IPE) is a highly purified (>96%) form of eicosapentanoic acid, a marine-derived omega-3 fatty acid known to reduce serum triglyceride levels. Experimental and human studies also support anti-atherosclerotic properties of IPE including antioxidant, anti-inflammatory, endothelial and plaque stabilizing effects. In the Reduction of Cardiovascular Events with Icosapent Ethyl-Intervention Trial (REDUCE-IT)l),the addition of 4 grams IPE daily resulted in a 25% reduction in cardiovascular events beyond statins and other standard of care therapies. ...
Contributors : David Milan ; Ling XiaoSeries Type : Expression profiling by high throughput sequencingOrganism : Mus musculusThe aim of this study is to perform transcriptome analysis on mouse left atrium tissue after long-term ibrutinib treatment or cardiac CSK knockout, in order to compared the enriched gene clusters.
Atrial fibrillation (AF) is common in patients with the left ventricular assist device (LVAD), but the little is known about the impact of AF on clinical outcomes. The aim of this study is to investigate the impact of AF on outcomes in patients with the HeartMate 3 (HM3) LVAD.
Falls and syncope are associated with increasing age and cause considerable morbidity and mortality in the elderly.1 Beyond age, traditionally recognized risk factors for falls include unsteady gait, muscle weakness, impaired cognition, and polypharmacy. Malik et al2 present a detailed systematic review evaluating the role of atrial fibrillation (AF) in falls/syncope and conclude that AF is independently associated with falls (odds ratio [OR], 1.19; 95% CI, 1.07-1.33) and syncope (OR, 1.88; 95% CI, 1.20-2.94) based on a meta-analysis of 7 and 3 observation al studies, respectively.
We report a case with uncommon late complication of this device causing erosion of the left ventricle, which open heart operation was carried out to repair the defect.
There is paucity of information on clinical characteristics and outcome of patients with familial atrial fibrillation (AF). The present study was aimed to compare clinical profile and outcome of familial AF with those of non-familial AF.
In patients with severe aortic stenosis (AS), atrial fibrillation (AF) is associated with increased long-term mortality after aortic valve replacement (AVR), which may be due to unfavorable hemodynamics in AF. We aimed to analyze the hemodynamic profile of patients with severe AS and AF versus sinus rhythm (SR).
To examine the potential association of atrial fibrillation (AF) to syncope and falls, we undertook a systematic review and meta-analysis given the increasing prevalence of AF in older adults as well as emerging data that it is a risk factor for dementia.
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