Epilepsy in the elderly: Unique challenges in an increasingly prevalent population

Publication date: January 2020Source: Epilepsy &Behavior, Volume 102Author(s): Nastasija Lezaic, Josée Roussy, Hélène Masson, Nathalie Jetté, Mark Robert KeezerAbstractElderly individuals (aged at least 60 or 65 years) represent a rapidly growing segment of the population. The incidence and prevalence of epilepsy is higher in this age group than in any other. Diagnosing epilepsy in the elderly can be challenging because the causes and clinical manifestations of seizures often differ as compared with younger individuals. Particular differential diagnoses, such as syncope and amyloid spells, are commonly encountered in the elderly population. A diagnosis of epilepsy has important implications in the older adult, many of which already present a variety of concomitant complex medical problems, such as cognitive impairment, comorbid cerebrovascular disease, and frailty. The treatment of epilepsy in the elderly is complicated by a variety of factors related to aging, including physiological changes, medical comorbidities, and polypharmacy. In this narrative review, we will address the descriptive epidemiology, clinical presentation, differential diagnosis, diagnostic evaluation, treatment, and prognosis of epilepsy in the elderly individual.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research

Related Links:

OBJECTIVE: In the general population, injury related to seizures often involves falls, head trauma, soft tissue injuries, burns and fractures. Additionally, postictal deleterious behavior changes can by experienced by patients. We seek to identify the risk...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Egress, Escape, Evacuation, Crowds Source Type: news
This study examines whether and how se...
Source: SafetyLit - Category: International Medicine & Public Health Tags: Ergonomics, Human Factors, Anthropometrics, Physiology Source Type: news
Publication date: Available online 26 January 2020Source: SeizureAuthor(s): Jacint Sala-Padro, Júlia Miró, Antoni Rodriguez-Fornells, Manolo Quintana, Noemi Vidal, Gerard Plans, Mila Santurino, Mercè Falip, Estela CàmaraAbstractPurposeOur aim was to study the microstructural architecture of the contralateral hippocampus to the affected side in patients with temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) and its relation with surgical outcome.MethodWe included 33 consecutive patients evaluated in our epilepsy surgery program during a five-year period. They underwent a presurgical MRI ...
Source: Seizure - Category: Neurology Source Type: research
A drug –drug interaction between cannabidiol and clobazam may explain why cannabidiol reduces the frequency of seizures in patients with a severe form of epilepsy, researchers have reported.
Source: The Pharmaceutical Journal - Category: Drugs & Pharmacology Source Type: research
ConclusionsA wearable EEG device with 2 bipolar channels simplifies the process of obtaining repeated SI quantification allowing a more accurate follow-up of spike activity in the clinical setting.
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
Source: Nutritional Neuroscience - Category: Nutrition Authors: Source Type: research
Temporal lobe epilepsy with hippocampal sclerosis (TLE-HS) is currently understood as a disease that originates in a largely distributed neuronal network, involving temporal and extratemporal structures [1]. Neuroimaging studies have mainly placed the focus on characterizing the affected hippocampus, since surgical removal of the mesial temporal structures has proven to be effective; however, approximately 40% of patients relapse [2].
Source: Seizure: European Journal of Epilepsy - Category: Neurology Authors: Source Type: research
ConclusionAutomatic quantification of myoclonic jerks using human pose and body movement analysis of patients’ videos is feasible and was found to be quite consistent with the accepted clinical gold standard quantification method. Based on the results of this study, the automatic analytical method should be further developed and validated to improve myoclonus severity follow-up for EPM1 patients.
Source: Seizure - Category: Neurology Source Type: research
Publication date: Available online 24 January 2020Source: SeizureAuthor(s): Hui-Hsien Pan, Tung-Wei Hung, Jeng-Dau Tsai, Hsuan-Ju Chen, Pei-Fen Liao, Ji-Nan SheuABSTRACTPurposeLittle is known about whether allergic disease is associated with a subsequent increased risk of childhood-onset epilepsy. We used a large, population-based cohort study to examine whether children with antecedent allergic rhinitis (AR) were associated with a subsequent increased risk of epilepsy.MethodsThis retrospective population-based cohort study was conducted by using data from the 2000–2012 Taiwan’s National Health Insurance Resear...
Source: Seizure - Category: Neurology Source Type: research
ConclusionFrom the available evidence, FS meets more of the criteria proposed for an acceptable label than other popular terms in the field. While the term FS is neutral with regard to etiology and pathology (particularly regarding whether psychological or not), other terms such as “dissociative”, “conversion”, or “psychogenic” seizures are not. In addition, FS can potentially facilitate multidisciplinary (physical and psychological) management more than other terms. Adopting a universally accepted terminology to describe this disorder could standardize our approach to the illness and fa...
Source: Epilepsy and Behavior - Category: Neurology Source Type: research
More News: Epidemiology | Epilepsy | Neurology