Should Urine-LAM Tests Be Used in TB Symptomatic HIV-Positive Patients When No CD4 Count Is Available? A Prospective Observational Cohort Study From Malawi
Background: Current eligibility criteria for urine lateral-flow lipoarabinomannan assay (LF-LAM) in ambulatory, HIV-positive patients rely on the CD4 count. We investigated the diagnostic yield of LF-LAM and the 6-month mortality in ambulatory, TB symptomatic, HIV-positive patients regardless of their CD4 count. Methods: We conducted a prospective, observational study that included all ambulatory, ≥15-year-old, TB symptomatic (cough, weight loss, fever, or night sweats) HIV-positive patients presenting at 4 health facilities in Malawi. Patients received a clinical examination and were requested urine LF-LAM, sputum microscopy, and Xpert MTB/RIF. TB was defined as bacteriologically confirmed if Xpert was positive. Results: Of 485 patients included, 171 (35.3%) had a CD4
BOSTON (CBS/CNN) – A new Chinese coronavirus, a cousin of the SARS virus, has infected more than 200 people since the outbreak began in Wuhan, China, in December. Boston’s Logan Airport is not currently screening passengers for the illness, a spokesman for Customs and Border Protection told WBZ-TV. That’s because there are no direct flights to Boston from that region. Additional health screening for coronavirus is in place at JFK Airport in New York, San Francisco International Airport and Los Angeles International Airport. The agency said the CDC has determined that coronavirus presents a low risk to the...
TUESDAY, Jan. 21, 2020 -- Little Johnny's cough has lasted for days, leaving Mom and Dad wondering if the symptoms warrant a trip to the doctor. A new study suggests that such parents may choose to skip that standard pediatric sick visit. Overall...
Pulmonary disease remains the most significant determinant of morbidity and mortality in cystic fibrosis (CF). Patients with CF typically experience progressive decline in lung function punctuated by pulmonary exacerbations , acute episodes characterized by worsened cough and sputum production and thickness, as well as decreases in pulmonary function, appetite, and weight. Over 34% of patients with CF are treated with IV antibiotics for an exacerbation each year ; median duration of hospitalization for these events is 9.3 days, and the median duration of IV antibiotics is 13 days .
(BEIJING) — Seventeen more people in central China have been diagnosed with a new form of viral pneumonia that has killed two patients and placed other countries on alert as millions of Chinese travel for Lunar New Year holidays. In total, 62 cases of the novel coronavirus have been identified in the city of Wuhan, where the virus appears to have originated. The Wuhan Municipal Health Commission reported the new cases in a statement Sunday. Nineteen of those individuals have been discharged from the hospital, while two men in their 60s — one with severe preexisting conditions — have died from the illness....
ConclusionIt is envisaged that the current review will add value to more scientific research on M. flabellifolius and enhance/promote the increased interest in the sustainable commercialization of M. flabellifolius herbal tea as well as lead to the validation of unverified ethnobotanical claims.Graphical abstract
ConclusionsAn advanced 3-D printing model provides affirmative information related to treatment strategy and is also a prospective tool for better doctor –patient communication regarding the disease.
Condition: Post-infectious Cough Interventions: Drug: PREDNISON Galepharm Tabl. 20 mg; Drug: placebo tablets Sponsors: University Hospital, Basel, Switzerland; Swiss National Science Foundation Not yet recruiting
Condition: Asthma Intervention: Sponsor: McMaster University Recruiting
Acute cardiogenic pulmonary oedema (ACPO) is one of the common causes of acute respiratory failure, constituting 10% –20% of acute heart failure syndromes and potentially causing death . Acute cardiogenic pulmonary oedema ACPO usually presents with sudden dyspnoea at rest, impaired exertion capacity, tachypnoea, tachycardia and hypoxia. Increased endogenous catecholamine levels and hypertension due to stress are common in cases with good left ventricular function. Cough is a frequent finding in these cases.
ConclusionsThe SAPB, as part of a multimodal analgesia regimen, is non ‐inferior in terms of 48‐hour opioid consumption compared to SPVB and is associated with improved functional measures in thoracic surgical patients.