Detailed Relationship Between Sympathetic Nerve Dysfunction and Quality of Life Following Left Ventricular Assist Device Implantation.

Detailed Relationship Between Sympathetic Nerve Dysfunction and Quality of Life Following Left Ventricular Assist Device Implantation. J Cardiovasc Nurs. 2020 Jan/Feb;35(1):11 Authors: Imamura T PMID: 31804247 [PubMed - in process]
Source: The Journal of Cardiovascular Nursing - Category: Nursing Authors: Tags: J Cardiovasc Nurs Source Type: research

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This study used a comprehensive battery of laboratory tasks to assess peripheral fiber function (cool/warm detection thresholds), pain sensitivity (eg, thresholds/tolerances), central sensitization (eg, temporal summation), and pain inhibition (conditioned pain modulation) in healthy, pain-free adults (N = 155 NAs, N = 150 non-Hispanic Whites [NHWs]). Multiple pain stimulus modalities were used (eg, cold, heat, pressure, ischemic, and electric), and subjective (eg, pain ratings and pain tolerance) and physiological (eg, nociceptive flexion reflex) outcomes were measured. There were no group differences on any measure, exce...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
This study aims to test the hypothesis that induced spinal sensitization could be more pronounced in patients affected by high-frequency migraine (HF-MIG) with respect to low-frequency migraine (LF-MIG). We enrolled 28 patients with LF-MIG (1-5 migraine days/month), 19 patients with HF-MIG (6-14 migraine days/month), and 21 healthy controls (HCs). Spinal sensitization was evaluated with the neurophysiological recording of the temporal summation threshold (TST) of the nociceptive withdrawal reflex at the lower limb. Temporal summation threshold was recorded at baseline and 30, 60, and 120 minutes after NTG administration (0...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
Low levels of catechol-O-methyltransferase (COMT), an enzyme that metabolizes catecholamines, and stress, which potentiates catecholamine release from sympathetic nerves, are fundamental to chronic functional pain syndromes and comorbid depression, which predominantly affect females. Here, we sought to examine the independent and joint contributions of low COMT and stress to chronic functional pain and depression at the behavioral and molecular level. Male and female C57BL/6 mice received sustained systemic delivery of the COMT inhibitor OR486 over 14 days and underwent a swim stress paradigm on days 8 to 10. Pain and depr...
Source: Pain - Category: Anesthesiology Tags: Research Paper Source Type: research
(CNN) — Marie Antoinette’s hair suddenly turned white before the ill-fated French queen was taken to the guillotine to have her head chopped off, according to some historical accounts. More modern reports refer to hair turning prematurely white in survivors of bomb attacks during World War II, while an Australian airline pilot saw his hair go gray in the months after landing a plane following a failure of all four engines in the early 1980s. While there’s been plenty of anecdotal evidence suggesting premature graying can be caused by extreme stress — whether this is true and how this happens isn&rsq...
Source: WBZ-TV - Breaking News, Weather and Sports for Boston, Worcester and New Hampshire - Category: Consumer Health News Authors: Tags: Boston News Health CNN Harvard University Source Type: news
When Ya-Chieh Hsu, professor of stem cell and regenerative biology at Harvard University and the Harvard Stem Cell Institute, wanted to figure out exactly what makes hair turn grey, she started with an obvious, albeit anecdotal, culprit: stress. There are well-known historical examples of the connection between stress and hair greying—Marie Antoinette’s coif reportedly blanched after she was captured during the French Revolution—and studies have even linked stress in animals to greying hair. But for the first time, Hsu and her colleagues figured out the biological reason why stress saps the pigment out of...
Source: TIME: Health - Category: Consumer Health News Authors: Tags: Uncategorized grey hair Stress Source Type: news
This study was conducted among healthy adolescents to assess the effects of a yoga breathing practice (Bhramari pranayama, Bhr.P) towards cardiac autonomic function using heart rate variability (HRV) parameters.MethodsOf the 730 eligible subjects screened, 520 healthy adolescents who met the inclusion and exclusion criteria were randomly assigned to either yoga breathing group (n = 260) or control group (n = 260). The yoga breathing group practiced Bhr.P. five days a week for a duration of six months while the control group continued with their daily routine without any intervention. Outcome mea...
Source: Integrative Medicine Research - Category: Complementary Medicine Source Type: research
We report the multidisciplinary and shared decision-making approach that resulted in successful surgical removal of 3 paragangliomas in a SDHD mutation carrier.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Laryngopharyngeal reflux and atypical manifestations of gastroesophageal reflux disease have a high economic and social burden in the United States. There is increasing research supporting the reflex theory and hypersensitivity syndrome underlying this disease pathophysiology. Novel diagnostic biomarkers have gained more traction in the search for a more reliable diagnostic tool, but further research is needed. Current standard-of-care treatment relies on proton pump inhibitor therapy. Antireflux surgery is usually not recommended. Neuromodulators and treatments targeting specific neuronal receptors are discussed. A diagno...
Source: Gastrointestinal Endoscopy Clinics of North America - Category: Gastroenterology Authors: Source Type: research
Scapulothoracic arthrodesis (STA) has been proposed for the treatment of painful scapular winging in patients with facioscapulohumeral muscular dystrophy (FSHD). However, the rate of osseous fusion is variable, and there is a theoretical risk of reduced respiratory function after bilateral STA.
Source: Journal of Shoulder and Elbow Surgery - Category: Orthopaedics Authors: Source Type: research
The regulation of the autonomic nervous system (ANS) can improve cognitive function in major depressive disorders (MDD). Heart rate variability (HRV) derives from the dynamic control of the ANS and reflects the balance between the activities of the sympathetic and parasympathetic nervous systems by measuring tiny changes in adjacent heart beats. Task-related HRV may reflect the association between the flexibility of cognition and ANS function. The study was to investigate the neural mechanism of interactions between ANS and cognitive function in MDD with Magnetoencephalography (MEG) measurements. Participants included 20 M...
Source: Frontiers in Psychiatry - Category: Psychiatry Source Type: research
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