British Hiker Survives Six-Hour Cardiac Arrest in & quot;Exceptional & quot; Case - Spanish Doctor British Hiker Survives Six-Hour Cardiac Arrest in & quot;Exceptional & quot; Case - Spanish Doctor

A 34-year-old British hiker was revived in Spain after a six-hour cardiac arrest brought on by severe hypothermia, with the low mountain temperatures that made her ill also helping to save her life in what a doctor described as an"exceptional case."Reuters Health Information
Source: Medscape Critical Care Headlines - Category: Intensive Care Tags: Cardiology News Source Type: news

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Publication date: January 2020Source: The Journal of Allergy and Clinical Immunology: In Practice, Volume 8, Issue 1Author(s): Anna Nowak-Wegrzyn, M. Cecilia Berin, Sam MehrFood protein-induced enterocolitis syndrome (FPIES) is a non–IgE-mediated food allergy that manifests with projectile, repetitive emesis that can be followed by diarrhea and may be accompanied by lethargy, hypotonia, hypothermia, hypotension, and metabolic derangements. FPIES usually starts in infancy although onset at older ages is being increasingly recognized. FPIES is not rare, with the cumulative incidence of FPIES in infants estimated to be ...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
In conclusion, isoflurane protected against BBB disruption caused by carbogen inhalation in mice and rats, but unlike isoflurane-mediated protection against ischemic BBB disruption, the effect could not be explained by anesthesia-induced hypothermia.
Source: NeuroReport - Category: Neurology Tags: Cellular, Molecular and Developmental Neuroscience Source Type: research
This study examined the possible upstream cellular signaling pathway associated with nitric oxide (NO)-mediated inhibition of phenylephrine-induced contraction in isolated rat aortae in response to mild hypothermia, with a particular focus on endothelial Rho-kinase. We examined the effects of mild hypothermia (33°C), wortmannin, Nω-nitro-L-arginine methyl ester (L-NAME), Y-27632, 1H-[1,2,4]oxadiazolo[4,3-a]quinoxalin-1-one (ODQ) and methylene blue, alone and combined, on phenylephrine-induced contraction in isolated rat aortae. Finally, we examined the effects of mild hypothermia, wortmannin, Y-27632 and L-NAME, ...
Source: International Journal of Medical Sciences - Category: Biomedical Science Tags: Int J Med Sci Source Type: research
Heme oxygenase (HO)-1 plays an important role during hibernation by catalyzing the degradation of heme to biliverdin/bilirubin, ferrous iron, and carbon monoxide, which activates the protective mechanisms against stress. In this context, it was important to analyze the metabolic processes of heme. Nevertheless, to date, no study has approached on biosynthesis of heme. Therefore, our study aims to understand the process of heme biosynthesis, which regulates cell survival in conditions of hypothermia and calorie restriction (CR). During hibernation, the mRNA levels of enzymes responsible for de novo heme biosynthesis were in...
Source: Frontiers in Physiology - Category: Physiology Source Type: research
Therapeutic hypothermia has been recommended for eligible patients after cardiac arrest (CA) in order to improve outcomes. Up to now, several comparative observational studies have evaluated the combined use o...
Source: Scandinavian Journal of Trauma, Resuscitation and Emergency Medicine - Category: Emergency Medicine Authors: Tags: Original research Source Type: research
The time is right to perform a randomized controlled trial (RCT) of neuroprotection for neonates with mild hypoxic-ischemic encephalopathy (HIE). According to published reports, more than 600 infants with mild HIE have undergone hypothermia at 33.5 °C for 72 hours.1-6 Data on neuroimaging findings following cooling for mild HIE from these reports are now becoming available. Depending on the cohort evaluated, whether retrospective or prospective, and whether infants received cooling or not, 11%-40% of infants with mild HIE have brain injury a nd watershed injury is seen more frequently than basal ganglia or thalamus injury.
Source: The Journal of Pediatrics - Category: Pediatrics Authors: Tags: Commentary Source Type: research
CONCLUSION: In children undergoing cardiac surgery in our department, the use of sevoflurane-balanced anesthesia during cardiopulmonary bypass showed no superiority of inhalational agents over total intravenous anesthesia with opioids and benzodiazepines preventing phases of superficial anesthesia, but a marked advantage for the postoperative ventilation time compared with total intravenous anesthesia. PMID: 31928325 [PubMed - as supplied by publisher]
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
Publication date: Available online 9 January 2020Source: Pharmacology &TherapeuticsAuthor(s): Andras Garami, Yury P. Shimansky, Zoltan Rumbus, Robson C.L. Vizin, Nelli Farkas, Judit Hegyi, Zsolt Szakacs, Margit Solymar, Alexandra Csenkey, Dan A. Chiche, Ram Kapil, Donald J. Kyle, Wade D. Van Horn, Peter Hegyi, Andrej A. RomanovskyAbstractAntagonists of the transient receptor potential vanilloid-1 (TRPV1) channel alter body temperature (Tb) in laboratory animals and humans: most cause hyperthermia; some produce hypothermia; and yet others have no effect. TRPV1 can be activated by capsaicin (CAP), protons (low pH), and h...
Source: Pharmacology and Therapeutics - Category: Drugs & Pharmacology Source Type: research
Publication date: Available online 6 January 2020Source: Air Medical JournalAuthor(s): Mathieu Pasquier, Oliver Hugli, Adam-Scott Feiner, Tomasz Darocha
Source: Air Medical Journal - Category: Emergency Medicine Source Type: research
This article is protected by copyright. All rights reserved. PMID: 31912503 [PubMed - as supplied by publisher]
Source: The Journal of Physiology - Category: Physiology Authors: Tags: J Physiol Source Type: research
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