A meta-analysis of the effects of therapeutic hypothermia in adult patients with traumatic brain injury

Therapeutic hypothermia management remains controversial in patients with traumatic brain injury. We conducted a meta-analysis to evaluate the risks and benefits of therapeutic hypothermia management in patien...
Source: Critical Care - Category: Intensive Care Authors: Tags: Review Source Type: research

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Conclusions: We determined that SG-SP1 directly interacts with FcεRI and propose SG-SP1 as a therapeutic candidate for mast cell-mediated allergic inflammatory disorders via inhibition of FcεRI signaling.
Source: Frontiers in Immunology - Category: Allergy & Immunology Source Type: research
Conclusion AKI is still a common complication of perinatal asphyxia despite treatment with therapeutic hypothermia. Identification of risk factors associated with the development of AKI in asphyxiated infants would be potentially beneficial to reduce morbidity and mortality. Besides perinatal risk factors, initial and 12-hour lactate concentrations can be used for the early prediction of AKI. [...] Thieme Medical Publishers 333 Seventh Avenue, New York, NY 10001, USA.Article in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: American Journal of Perinatology - Category: Perinatology & Neonatology Authors: Tags: Original Article Source Type: research
This article combines well-established and contemporary information to summarize a systems-based approach to traditional neonatal physiology.
Source: Anaesthesia and intensive care medicine - Category: Anesthesiology Source Type: research
Alcohol poisoning is a serious medical emergency due to the overconsumption of alcohol that can result in death. Overconsumption of alcohol affects many systems in the body. The liver, which works to eliminate toxins from the body, is not able to keep up with the high amount being ingested. In turn, the central nervous system becomes so depressed to the point that it cannot perform its normal, essential functions such as beating the heart and breathing. There are many factors that can determine whether or not an individual could suffer from alcohol poisoning, such as: Rate of alcohol consumption Tolerance and dependency ...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Alcohol Alcohol Rehab Information Alcoholism Detox Resources for Alcohol and Drugs/Opiates alcohol abuse alcohol detox alcohol treatment alcohol treatment center alcohol treatment facility Source Type: blogs
AbstractThe morphosis from open surgeries to minimally invasive procedures is in greater part owing to the development of robotics. There has been a hiking popularity of robotic assistance for surgeries in recent years. Though a minimally invasive approach for surgery, it poses major challenges for an anesthesiologist that compound further for pediatric patients. The need of the hour for an anesthesiologist is to have a scrupulous knowledge and understanding of the associated anatomical and physiological considerations in case of pediatric patients. Major anesthetic concerns include restricted patient access, physiologic c...
Source: Journal of Anesthesia - Category: Anesthesiology Source Type: research
We report our experience of a case series of six neonates who underwent therapeutic hypothermia for hypoxic-ischemic encephalopathy during extracorporeal life support. We also report long-term neurodevelopmental follow-up from 6 to 24 months and add to the current body of evidence regarding feasibility, clinical experience, and short-term complications. PMID: 31971073 [PubMed - as supplied by publisher]
Source: Perfusion - Category: Cardiovascular & Thoracic Surgery Authors: Tags: Perfusion Source Type: research
AbstractContraindications to liver transplantation are gradually narrowing down. Cardiac illness and chronic liver disease may manifest independently or may be superimposed on each other due to shared pathophysiology. Cardiac surgery involving the cardiopulmonary bypass in patients with Child ‐Pugh Class C liver disease is associated with a high risk of perioperative morbidity and mortality. Liver transplantation involves hemodynamic perturbations, volume shifts, coagulation abnormalities, electrolyte disturbances, and hypothermia, which may prove fatal in patients with cardiac illness depending upon the severity. Additi...
Source: Journal of Hepato-Biliary-Pancreatic Sciences - Category: Gastroenterology Authors: Tags: REVIEW ARTICLE Source Type: research
ConclusionsFor patients without aortic dissection and who require more than 30 minutes of circulatory arrest, optimal cerebral protection strategies are deep hypothermia with either antegrade or retrograde cerebral perfusion and moderate hypothermia with antegrade cerebral perfusion.
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
Source: Journal of Maternal-Fetal and Neonatal Medicine - Category: Perinatology & Neonatology Authors: Source Type: research
This article was corrected online.
Source: JAMA Pediatrics - Category: Pediatrics Source Type: research
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