Reduced microRNA 375 in colorectal cancer upregulates metadherin-mediated signaling.

CONCLUSION: Our findings suggest that suppressing MIR375 expression in CRC regulates cell proliferation and angiogenesis by increasing MTDH expression. Thus, MIR375 may be of therapeutic value in treating human CRC.
PMID: 31802830 [PubMed - in process]

Source: World Journal of Gastroenterology : WJG - November 27, 2019 Category: Gastroenterology Authors: Han SH, Mo JS, Park WC, Chae SC Tags: World J Gastroenterol Source Type: research