High homogeneity of mismatch repair deficiency in advanced prostate cancer

ConclusionsThe absence of intratumoral heterogeneity for the MMR status suggests that MSI occurs early in prostate cancer. It is concluded that MMR analysis on limited biopsy material by IHC is sufficient to estimate the MMR status of the entire cancer mass.
Source: Virchows Archiv - Category: Pathology Source Type: research