Graft Survival After Penetrating and Endothelial Keratoplasty in Iridocorneal Endothelial Syndrome

Conclusions: The results indicate no difference in graft survival between PK and EK for ICE syndrome. Graft survival in ICE syndrome is intermediate between that of FED and PBK.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research

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Conclusions: Creating a central descemetorhexis with a slit-lamp Nd:YAG laser proved feasible in vitro. This new technical approach might open the door to a customized in vivo “descemetorhexis-only” treatment for Fuchs endothelial corneal dystrophy eyes, while avoiding the risks associated with intraocular surgery.
Source: Cornea - Category: Opthalmology Tags: Basic Investigation Source Type: research
Publication date: Available online 30 December 2019Source: Redox BiologyAuthor(s): Matthew Lovatt, Khadijah Adnan, Viridiana Kocaba, Martin Dirisamer, GaryS.L. Peh, Jodhbir S. MehtaAbstractCorneal transparency is maintained by a monolayer of corneal endothelial cells. Defects in corneal endothelial cells (CEnCs) can be rectified surgically through transplantation. Fuchs’ endothelial corneal dystrophy (FECD) is the foremost cause of endothelial dysfunction and the leading indication for transplantation. Increased sensitivity of CEnCs to oxidative stress is thought to contribute to the pathogenesis of FECD through incr...
Source: Redox Biology - Category: Biology Source Type: research
CONCLUSION: Introduction of DMEK in a single center can be implemented in a relatively short period of time, becoming the most popular surgical procedure in corneal transplantation. A possible factor encouraging this change is the availability of eye bank-delivered precut tissue, and standardization of donor preparation and host surgical steps, optimizing surgical time in the operating room. This trend should lead to better visual outcomes, faster recovery times, and eventually to a higher surgical volume per year. PMID: 31831273 [PubMed - as supplied by publisher]
Source: Journal Francais d Ophtalmologie - Category: Opthalmology Tags: J Fr Ophtalmol Source Type: research
Conclusion: A routine ophthalmic follow-up is recommended for all patients with established or suspected amyloidosis, independent of the biochemical type of the amyloid. Close collaboration between the ophthalmologist and the internist will facilitate a more precise diagnosis of ocular involvement in amyloidosis and allow the multidisciplinary management of these patients.Abbreviations: CD: corneal dystrophy; CLA: corneal lattice amyloidosis; CNS: central nervous system; CT: computed tomography; FAP: familial amyloidotic polyneuropathy; GDLCD: gelatinous drop-like corneal dystrophy; GLN: gelsolin; LCD: lattice corneal dyst...
Source: Seminars in Ophthalmology - Category: Opthalmology Tags: Semin Ophthalmol Source Type: research
Conclusions: DM suturing can reattach DM, especially in moderate to severe, recurrent DMD with fewer postoperative complications and thereby reduce the need for corneal transplantation.
Source: Cornea - Category: Opthalmology Tags: Clinical Science Source Type: research
Conclusions: Epithelial ingrowth may occur after a corneal endothelium transplant. There have been multiple reports of epithelial ingrowth after Descemet stripping automated endothelial keratoplasty, but this particular case report suggests that epithelial ingrowth may also occur after DMEK. In this case, PK solved the complication.
Source: Cornea - Category: Opthalmology Tags: Case Report Source Type: research
ConclusionsBK was the first cause of keratoplasty with almost half of the cases, and keratoconus was relegated to sixth place with less than 5%. In comparison, in a study from eye banks from the US, BK was the second and keratoconus was the third indication for corneal grafts. The frequency of endothelial lamellar techniques in our institution decreased from 2012 to 2016. This could have been related to both the long time that the patients had to be on a waiting list, which made them unsuitable candidates for this technique, due to stromal fibrosis, and to the fact that surgeons of our institution had less experience with ...
Source: International Ophthalmology - Category: Opthalmology Source Type: research
Abstract Patients with gelatinous drop-like corneal dystrophy need to be effectively managed as the disease is severely debilitating in view of associated pho-tophobia and glare. Here, we report a rare case of gelatinous drop-like corneal dystrophy effectively managed by intraoperative anterior segment optical coherence tomography-guided manual deep anterior lamellar keratoplasty in 1 eye and sutureless fibrin glue-aided, microkeratome-assisted automated lamellar therapeutic keratoplasty in the other eye. The patient, a 22-year old man, presented with gradual diminution of vision associated with foreign body sensa...
Source: Experimental and Clinical Transplantation : official journal of the Middle East Society for Organ Transplantation - Category: Transplant Surgery Authors: Tags: Exp Clin Transplant Source Type: research
In this issue of JAMA Ophthalmology, Ang et al describe a prespecified secondary outcome of the Descemet Endothelial Thickness Comparison Trial (DETECT), a study designed to compare visual acuity outcomes from ultrathin Descemet stripping endothelial keratoplasty (UT-DSAEK) and Descemet membrane endothelial keratoplasty (DMEK). The main and primary study outcome was that DMEK eyes saw 1.4 lines better than UT-DSAEK eyes at 12 months. Although visual acuity is the traditional functional measure of surgical success in ophthalmology, increasingly patient-reported outcomes, particularly those measuring vision-related quality o...
Source: JAMA Ophthalmology - Category: Opthalmology Source Type: research
Keratoconus is the most common corneal dystrophy in the Western world, frequently leading to severely impaired vision, most commonly in late childhood to early adulthood. Up to 25% of individuals with keratoconus will progress to a disease stage in which sharp visual acuity cannot be achieved anymore with vision correction and surgery is required. In recent years, corneal crosslinking (CXL) has become an established treatment to reduce the progression of keratoconus, thus eventually avoiding the need for corneal transplant. This underlines the importance of an early identification of patients at risk. The current clinical ...
Source: JAMA Ophthalmology - Category: Opthalmology Source Type: research
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