Glis3 as a critical regulator of thyroid primordium specification.

CONCLUSIONS: Our results demonstrate that glis3, within the SHH pathway, appears to determine the number of endodermal cells committed to a thyroid fate. This is the first evidence of the involvement of glis3 in TD, increasing our knowledge on the genetic bases of CH pathogenesis. PMID: 31797737 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - Category: Endocrinology Tags: Thyroid Source Type: research