Reflections on Digestions and Other Corporealities in Artists ’ Books
AbstractWith an avid attention to the valuing of embodiment and a championing of the re-emergence of the body as site for discussions of knowledge and knowing, this essay shares aspects of my practice that engage a performative, haptic, situated engagement with the body through the artist ’s book. The motivation for the creation of my bookworks was an interest in manifesting situated knowing and embodied ways of becoming. Engaging form, materiality, and bodily history, my artists’ books explore the processes and metaphors of digestion and in one example, mindfulness practice. In libraries and collections with links to health, my artists’ books can be experienced in teaching and research contexts to examine the body, health, illness and wellbeing. This essay focuses on my books which communicate embodied knowledge in several ways: through phenomenological writing to give e xpression to my irritable bowel syndrome (IBS) and how it impacts on my teaching practice inReflection on Digestion; through bodily material ofEntrail Troyen; through the image of the digestive system inOn Innards,Reflection on Digestion, andEntrail Troyen, particularly the concertina form emulating the undulations of the intestines; and through images of found objects that resemble the bowels inHuwawa in the Everyday.
CONCLUSION: MiR-510 downregulation in intestinal tissue might contribute to PI-IBS via targeting PRDX1. The results of this study will not only enrich the pathogenesis of PI-IBS but also make us understand the biological activity of miR-510 and provide important experimental basis for PI-IBS clinical treatment targeting miR-510. PMID: 31934286 [PubMed]
Patients in GP surgeries in Bristol are being invited to take part in a large trial of low-dose amitriptyline for irritable bowel syndrome (IBS) lead by researchers from the universities of Bristol, Leeds and Southampton.
Conclusions: Stool microbial diversity and composition are linked to daily extraintestinal symptoms, stool consistency, and QOL in women with IBS.
In the absence of a well-established therapeutic approach, patients with irritable bowel syndrome seek alternative strategies such as probiotics.
Publication date: 9 January 2020Source: Cell, Volume 180, Issue 1Author(s): Fanny Matheis, Paul A. Muller, Christina L. Graves, Ilana Gabanyi, Zachary J. Kerner, Diego Costa-Borges, Tomasz Ahrends, Philip Rosenstiel, Daniel MucidaSummaryEnteric-associated neurons (EANs) are closely associated with immune cells and continuously monitor and modulate homeostatic intestinal functions, including motility and nutrient sensing. Bidirectional interactions between neuronal and immune cells are altered during disease processes such as neurodegeneration or irritable bowel syndrome. We investigated the effects of infection-induced inf...
Conclusions: Phloroglucinol could be a safe and beneficial option for the management of overall IBS symptoms in patients with IBS-D. Further large scaled studies are warranted. PMID: 31917916 [PubMed]
Authors: Steinsvik EK, Valeur J, Hausken T, Gilja OH Abstract Background/Aims: Dyspeptic symptoms are common in patients with functional gastrointestinal (GI) disorders, and may be related to visceral hypersensitivity. We aim to explore the relation between visceral hypersensitivity by using an ultrasonographic meal test and questionnaires in patients with irritable bowel syndrome (IBS) and/or functional dyspepsia (FD). Methods: Patients (FD, n = 94; IBS, n = 88; IBS + FD, n = 66, healthy controls [HC], n = 30) were recruited consecutively and examined with ultrasound of the proximal and distal stomach after dr...
Authors: Lee HS PMID: 31917911 [PubMed]
(Rockefeller University) For some unlucky people, a bout of intestinal distress like traveler's diarrhea leads to irritable bowel syndrome. Recent discoveries have given scientists a better idea of how this happens, and potential leads for new treatments.
Traditional treatments for irritable bowel syndrome (IBS) are supported only by limited data from trials with significant risk of bias, according to a systematic review and network meta-analysis.Reuters Health Information