A case of CNS aspergillosis in a patient with chronic lymphocytic leukemia on first-line ibrutinib therapy

We present a case of CNS aspergillosis in a CLL patient on first line ibrutinib therapy. We summarize existing case reports and case series of invasive aspergillosis in patients on ibrutinib, the pathogenesis of invasive aspergillosis, and discuss the clinical controversies regarding anti-fungal prophylaxis in this population.
Source: Medical Mycology Case Reports - Category: Biology Source Type: research