Prostate cancer non-ascitic peritoneal carcinomatosis after robot-assisted laparoscopic radical prostatectomy: three case reports and review of the literature

Robot-assisted laparoscopic radical prostatectomy (RALRP) is one of the treatment options for localized prostate cancer, with an excellent disease control rate. However, these patients can experience late disease recurrence with metastatic dissemination. Peritoneal metastases are an uncommon recurrence site. Here, we discuss three cases of peritoneal metastases following RALRP and the mechanisms of peritoneal invasion. Through a literature review and our case reports, we postulate the existence of two distinct mechanisms of peritoneal invasion: one being iatrogenic, following a laparoscopic surgery with a well differentiated prostate cancer at a non-advanced stage of the disease, the other involving the natural course of poor-prognosis tumours, even without surgery.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research

Related Links:

Conclusion: Our study demonstrated that the aberrant expression of CDCA gene family members plays an indispensable role in tumorigenesis. PMID: 31955607 [PubMed - as supplied by publisher]
Source: Future Medicine: Biomarkers in Medicine - Category: Internal Medicine Tags: Biomark Med Source Type: research
Publication date: Available online 20 January 2020Source: Carbohydrate PolymersAuthor(s): Nadezhda E. Ustyuzhanina, Maria I. Bilan, Andrey S. Dmitrenok, Alexander S. Shashkov, Nora M.A. Ponce, Carlos A. Stortz, Nikolay E. Nifantiev, Anatolii I. UsovAbstractFucosylated chondroitin sulfate (FCS) HeSp was isolated from the Patagonian sea cucumber Hemioedema spectabilis. Ion-exchange chromatography was applied for purification of the FCS from the crude extract of sulfated polysaccharides. Analysis of monosaccharide and sulfate content of HeSp revealed the molar ratio of GlcA:GalNAc:Fuc:SO3Na as 1.15:1:1.1:3.9. Molecular weight...
Source: Carbohydrate Polymers - Category: Biomedical Science Source Type: research
Robot-assisted laparoscopic radical prostatectomy is one of the treatment options for localized prostate cancer, with an excellent disease control rate. However, these patients can experience late disease recurrence with metastatic dissemination. Peritoneal metastases are an uncommon recurrence site. Here, we discuss 3 cases of peritoneal metastases following robot-assisted laparoscopic radical prostatectomy and the mechanisms of peritoneal invasion. Through a literature review and our case reports, we postulate the existence of 2 distinct mechanisms of peritoneal invasion: one being iatrogenic, following a laparoscopic su...
Source: Urology - Category: Urology & Nephrology Authors: Tags: Review Article Source Type: research
Rationale: The problem of the coexistence of gastrointestinal stromal tumor (GIST) with other neoplasms is complex, and carcinomas of prostate is one of the common types of GIST-associated cancers. Doubling time of GIST is about 3.9 months for high-risk GIST, and the treatment paradigm for GIST has required the integration of surgery and molecular therapy. Patient concerns: A 70-year-old man with postoperative history of prostate cancer experienced fast-growing malignant jejunal GIST with multiple peritoneal metastases within 1 year. Diagnoses: Enhanced computed tomography (CT) detected a neoplasm of small intestin...
Source: Medicine - Category: Internal Medicine Tags: Research Article: Clinical Case Report Source Type: research
We report a case of urachus metastases showed on 68Ga-PSMA PET/CT performed for biochemical recurrence with a very low PSA level at 0.50 ng/mL.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Publication date: Available online 12 August 2018Source: Urology Case ReportsAuthor(s): Félix Couture, Joshua Chin, Jaron Chong, Simon Tanguay
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
We report a case of 68Ga-PSMA PET/MR–positive peritoneal metastasis as site of primary relapse after definitive PCa treatment in a 58-year-old man with a prostate-specific antigen of 30 ng/mL at time of the study. Exploratory laparoscopy and subsequent histopathologic examination confirmed nonascitic peritoneal PCa carcinomatosis.
Source: Clinical Nuclear Medicine - Category: Nuclear Medicine Tags: Interesting Images Source Type: research
Conclusion: F-18 FDG PET/CT has high diagnostic accuracy for detection of residual/recurrent disease in stomach cancer after treatment. Metachronous primary malignancy may also be incidentally detected. Research Support: N A
Source: Journal of Nuclear Medicine - Category: Nuclear Medicine Authors: Tags: GI-Non-colorectal Source Type: research
We present a case of non-ascitic omental metastasis of prostate cancer without any bone metastases. Furthermore, this patient has had two negative measurements of circulating tumor cells (CTCs) in the blood, suggesting a non-hematogenous route of metastasis to the omentum.
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
Abstract The authors present a rare case of prostate adenocarcinoma with peritoneal carcinomatosis demonstrated by F‐18 FDG PET/CT imaging. Traditionally, prostate cancer metastasizes to bones, lung, liver, pleura, and adrenal glands. The peritoneal carcinomatosis, seen in this case, may mimic dissemination of malignancy originating from the gastrointestinal tract, ovaries, breasts, lungs, and uterus.
Source: Journal of Gastroenterology and Hepatology - Category: Gastroenterology Authors: Tags: Education and Imaging ‐ Gastroenterology Source Type: research
More News: Cancer | Cancer & Oncology | Carcinoma | Laparoscopy | Peritoneal Cancer | Prostate Cancer | Prostatectomy | Urology & Nephrology