Characterizing the metabolic perturbations induced by activity-based anorexia in the C57Bl/6 mouse using 1H NMR spectroscopy

Anorexia nervosa (AN) is a severe psychological and potentially life-threatening eating disorder. The activity-based anorexia (ABA) mouse model is commonly used to investigate physiological abnormalities associated with this disorder. Characterizing the holistic biochemical alterations induced by anorexia is essential to understanding AN pathophysiology as well as to define biomarkers for prognosis.

Source: Clinical Nutrition - December 4, 2019 Category: Nutrition Authors: Jonathan Breton, Natasa Giallourou, Severine Nobis, Aline Morin, Najate Achamrah, Alexis Goichon, Liliana Belmonte, Pierre Dechelotte, Jean-Luc do Rego, Mo ïse Coëffier, Jonathan Swann Tags: Original article Source Type: research