White matter integrity underlying depressive symptoms in dementia caregivers

Depression symptoms in dementia caregivers (dCGs) increase the major depressive disorder risk.1 While the neurobiology of depression in dCGs has only indirectly been examined,2,3 numerous studies have examined the brain structural correlates of depression in older adults (without regard to caregiving). Patients with depression differ in several aspects of white matter connectivity4 potentially partially due to cerebrovascular disease.5 Meta-analytic6 evidence demonstrates that people with affective disorders tend to have lower white matter integrity in frontolimbic, frontostriatal, and medial temporal networks.
Source: The American Journal of Geriatric Psychiatry - Category: Geriatrics Authors: Tags: Brief Report Source Type: research

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__________ We are pleased to share a fantastic professional development opportunity offered by the Luria Neuroscience Institute and featuring renowned neuropsychologist Elkhonon Goldberg, Ph.D., ABPP. Inaugural 5‑day Goldberg Brain-Mind Symposium (February 17–21st, 2020): Dr. Goldberg has been a frequent visitor to Bali for 30 years and is currently engaged in cross-cultural neuroscience research with two major Indonesian universities. He personally designed this unique and comprehensive event to discuss cutting edge cognitive neuroscience and state-of-the-art clinical insights with a small group of participants in...
Source: SharpBrains - Category: Neuroscience Authors: Tags: Cognitive Neuroscience Health & Wellness Professional Development Bali discount code Elkhonon-Goldberg Executive-Functions frontal-lobes Goldberg Brain-Mind Symposia Luria Neuroscience Institute neuropsychologist webinar sequence Source Type: blogs
With Christmas behind us and the winter months stretching out ahead, for many people this part of the year can feel particularly miserable — and most especially if they suffer with Seasonal Affective Disorder. While it’s crucial to head to the doctor if you are finding it difficult to cope, there are evidence-backed self-help methods to boost our mood during winter, which can help us to tackle the January blues and no longer feel as if life is on hold until Spring.  Stay Social It can be tempting to hide away in winter, and a variety of factors can make it difficult for people to socialize even if they wan...
Source: World of Psychology - Category: Psychiatry & Psychology Authors: Tags: Mental Health and Wellness New Year's Self-Help Seasonal Affective Disorder Winter Blues Source Type: blogs
(Regenstrief Institute) In the first randomized controlled trial to evaluate pros and cons of population screening for dementia, Regenstrief Institute and Indiana University School of Medicine researchers found no harm, as measured by patient reported depressive and anxiety symptoms, from screening for Alzheimer's disease and related dementia in diverse rural, suburban and urban primary care clinics.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
ConclusionsResults revealed expert consensus and literature review agreement on a number of common modifiable risk factors for T2DM and dementia, as well as agreement on brain-related complications of diabetes. A number of other proposed shared risk factors did not reach consensus agreement suggesting a need for more high-quality studies to add to the evidence base.
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
Abstract Economics and mental health are intertwined. Apart from the accumulating evidence of the huge economic impacts of mental ill-health, and the growing recognition of the effects that economic circumstances can exert on mental health, governments and other budget-holders are putting increasing emphasis on economic data to support their decisions. Here we consider how economic evaluation (including cost-effectiveness analysis, cost-utility analysis and related techniques) can contribute evidence to inform the development of mental health policy strategies, and to identify some consequences at the treatme...
Source: World Psychiatry - Category: Psychiatry Authors: Tags: World Psychiatry Source Type: research
DISCUSSION: f-bvFTD and s-bvFTD cases are clinically similar, suggesting the generalizability of novel biomarkers, therapies, and clinical tools developed in either form to the other. PMID: 31914226 [PubMed - in process]
Source: The Journal of Alzheimers Association - Category: Psychiatry Tags: Alzheimers Dement Source Type: research
by Sofie Holmquist, Anna Nordstr öm, Peter Nordström BackgroundDepression is associated with an increased risk of dementia. However, short follow-up times and lack of adjustment for familial factors in previous studies could influence this association. The purpose of the present study was to investigate the association between depression and subsequent dementia, while controlling for familial factors and with a follow-up of over 35 years. Methods and findingsTwo cohorts were formed from all individuals aged 50 years or older living in Sweden as of 31 December 2005 (n = 3,341,010). The Swedish National Patient Reg...
Source: PLoS Medicine - Category: Internal Medicine Authors: Source Type: research
Ipsit Vahia, medical director at McLean Hospital, discusses how data and tech can help with early interventions in conditions such as dementia, depression and loneliness.
Source: Healthcare ITNews Videos - Category: Information Technology Tags: Connected Health Population Health Source Type: video
Notley This systematic review commissioned by the UK Department for the Environment, Food and Rural Affairs (Defra), considers how the evidence base for noise effects on health has changed following the recent reviews undertaken for the WHO Environmental Noise Guidelines. This systematic review assesses the quality of the evidence for environmental noise effects on mental health, wellbeing, and quality of life; birth and reproductive outcomes; and cognition for papers published since the WHO reviews (mid-2015 to March 2019), as well as for cancer and dementia (January 2014 to March 2019). Using the GRADE methodology (G...
Source: International Journal of Environmental Research and Public Health - Category: Environmental Health Authors: Tags: Article Source Type: research
Why does your teenager drive you crazy? A new study used MRI tools such as...Read more on AuntMinnie.comRelated Reading: AI-based model aids fMRI in ADHD detection MRI illuminates causes of depression fMRI shows how brains rebound from hemispherectomy fMRI differentiates Gulf War illness from chronic fatigue fMRI maps show dementia spreading through brain networks
Source: AuntMinnie.com Headlines - Category: Radiology Source Type: news
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