Association between long-term occupational manganese exposure and bone quality among retired workers.

Association between long-term occupational manganese exposure and bone quality among retired workers. Environ Sci Pollut Res Int. 2019 Dec 03;: Authors: Li D, Ge X, Liu Z, Huang L, Zhou Y, Liu P, Qin L, Lin S, Liu C, Hou Q, Li L, Cheng H, Ou S, Wei F, Shen Y, Zou Y, Yang X Abstract Despite well documents for manganese-induced neurological deficits, limited researches are available for effects of manganese (Mn) exposure on the bone. Here we aimed to explore the associations between long-term occupational Mn exposure and bone quality among retired workers. We conducted a cross-sectional study of 304 exposed subjects (n, male = 161 and female = 143) and 277 control retired workers (n, male = 65 and female = 212) recruited from a ferromanganese refinery. Self-reported occupation types were used as exposure classification confirmed by expert consultation. Bone quality was measured by quantitative ultrasound (QUS). In sex-stratified analyses throughout, stiffness index (SI) and T-score levels of the participants in the highest exposed group [tertile 3 of Mn cumulative exposure index (Mn-CEI)] were significantly lower as compared with the control group among female workers (SI, mean, 61.60 vs. 68.17; T-score, mean, -3.01 vs. -2.34, both P  0.05). Our results suggest that female retired workers in the highest Mn-exposed model (tertile 3 of Mn-CEI) potentially experience a higher risk of d...
Source: Environmental Science and Pollution Research International - Category: Environmental Health Authors: Tags: Environ Sci Pollut Res Int Source Type: research

Related Links:

ABSTRACTInvestigations into the effects of bone ‐targeted exercise programs on musculoskeletal health and function in men are limited. The purpose of the Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men (LIFTMOR‐M) trial was to examine the efficacy and safety of two novel, supervised, eight‐month, twice‐wee kly exercise programs in middle‐aged and older men with low BMD. Men with low proximal femur and/or LS BMD were recruited and randomized to high‐intensity progressive resistance and impact training (HiRIT) or machine‐based isometric axial compression (IAC). Intervention resp...
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Clinical Trial Source Type: research
AbstractPurpose of ReviewThis review discusses imaging modalities for fracture repair assessment, with an emphasis on pragmatic clinical and translational use, best practices for implementation, and challenges and opportunities for continuing research.Recent FindingsSemiquantitative radiographic union scoring remains the clinical gold standard, but has questionable reliability as a surrogate indicator of structural bone healing, particularly in early-stage, complex, or compromised healing scenarios. Alternatively, computed tomography (CT) scanning enables quantitative assessment of callus morphometry and mechanics through ...
Source: Current Osteoporosis Reports - Category: Orthopaedics Source Type: research
ABSTRACTInvestigations into the effects of bone ‐targeted exercise programs on musculoskeletal health and function in men are limited. The purpose of the Lifting Intervention For Training Muscle and Osteoporosis Rehabilitation for Men (LIFTMOR‐M) trial was to examine the efficacy and safety of two novel, supervised, eight‐month, twice‐wee kly exercise programs in middle‐aged and older men with low BMD. Men with low proximal femur and/or LS BMD were recruited and randomized to high‐intensity progressive resistance and impact training (HiRIT) or machine‐based isometric axial compression (IAC). Intervention resp...
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Clinical Trial Source Type: research
ConclusionHighest platelet counts within the normal range are significantly associated with osteopenia and osteoporosis in middle-aged and elderly people.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research
Abstract OBJECTIVE: This is a systematic review about the effects of low-intensity pulsed ultrasound (LIPUS) on stem cells differentiation. BACKGROUND DATA: In latest studies, several types of stem cells from different sources in the body have been used. These stem cells should be strictly certified and promoted for cell therapies before medical application. Low intensity pulsed ultrasound (LIPUS) has been extensively used in treatment centers and research to promote stem cells differentiation, function and proliferation. MATERIALS AND METHODS: We searched in PubMed, Google Scholar, Medline, and Scopus d...
Source: Current Stem Cell Research and Therapy - Category: Stem Cells Authors: Tags: Curr Stem Cell Res Ther Source Type: research
ConclusionsQUS of the calcaneus confidently out ruled low BMD in individuals with axSpA, reducing the need for onward DXA referral by up to 27%. QUS is promising as a non-invasive triage tool in the assessment of osteoporosis in adults with axSpA.Key Points•Osteoporosis is common in axial spondyloarthropathy (SpA), but evaluation of bone health is suboptimal in this population.•Quantitative ultrasound (QUS) of the calcaneus can out rule low bone mineral density in individuals with axial SpA, reducing the need for DXA assessment.•QUS is a promising non-invasive triage tool in the assessment of bone health in axial SpA.
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
The aging process is characterized by the chronic inflammatory status called “inflammaging”, which shares major molecular and cellular features with the metabolism-induced inflammation called “metaflammation.” Metaflammation is mainly driven by overnutrition and nutrient excess, but other contributing factors are metabolic modifications related to the specific body composition (BC) changes occurring with age. The aging process is indeed characterized by an increase in body total fat mass and a concomitant decrease in lean mass and bone density, that are independent from general and physiological flu...
Source: Frontiers in Endocrinology - Category: Endocrinology Source Type: research
This article is protected by copyright. All rights reserved.
Source: Journal of Bone and Mineral Research - Category: Orthopaedics Authors: Tags: Original Article Source Type: research
ConclusionsThese studies support unique functions for type-H vessels in the bone that may enable new therapeutic approaches to osteoporosis.
Source: Archives of Orthopaedic and Trauma Surgery - Category: Orthopaedics Source Type: research
Take the challenge. Answers Biosimilars Methotrexate Time Presenting problem Ultrasound guidance International Classification of Diseases Current Procedural Terminology Trigger points Osteoporosis Osteoarthritis
Source: The Rheumatologist - Category: Rheumatology Authors: Tags: Billing/Coding From the College Evaluation and Management infliximab Source Type: research
More News: Brain | Environmental Health | Manganese | Neurology | Neuroscience | Occupational Health | Orthopaedics | Osteoporosis | Science | Study | Ultrasound